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Found 739 clinical trials
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality …

  • 0 views
  • 25 Aug, 2023
  • 1 location
The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty

This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery. Half of the participants will be randomized into the exercise group, while the other half will be randomized into the control group.

  • 0 views
  • 16 Feb, 2024
  • 1 location
To Assess the Efficiency and Satisfaction of Pharmacist Giving Patient-centred Advice on Telephone Consultation in TB Patients: Experience of the COVID-19 Pandemic

The COVID-19 pandemic might be an opportunity to review and refine our practices in anti TB treatment. For the follow-up of selected patients, telephone consultations may be efficient and cost-effective. The aim of the study is to assess the efficiency and the satisfaction with telephone consultation for the pharmacist and …

covid-19
smear
  • 0 views
  • 05 Aug, 2020
The Effect of Dupilumab on Lung Function and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma

  • To evaluate safety of dupilumab
  • ul>

    leukotriene receptor antagonist
    pulmonary function test
    ct scan
    fractional exhaled nitric oxide
    dupilumab
    • 0 views
    • 12 Nov, 2020
    • 6 locations
    Safety Pharmacokinetics and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation

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    Secondary Objectives:

    <ul>
  • Phase 2: To characterize the safety profile of isatuximab in kidney transplant candidates.
  • sar650984
    kidney transplant
    isatuximab
    diphenhydramine
    nephropathy
    • 0 views
    • 12 Nov, 2020
    • 3 locations
    First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

    Primary Objectives:

    <ul>
  • Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B
  • Dose Expansion Part B: To assess …

    carfilzomib
    line of therapy
    stem cell transplantation
    therapy
    refractory multiple myeloma
    • 0 views
    • 04 Dec, 2020
    • 8 locations
    CIML NK Cell in Head & Neck Cancer

    This research study involves the following drugs and biologics:

    <ul>
  • CIML NK donor cells
  • IL-15 superagonist
  • Ipilimumab
  • ul>

    biological therapy
    ipilimumab
    head and neck cancer
    biologics
    squamous cell carcinoma of head and neck
    • 0 views
    • 16 Feb, 2024
    • 1 location
    Lorlatinib Combinations in Lung Cancer

    This research study is evaluating Lorlatinib in combination with Crizotinib or Binimetinib as a possible treatment for either anaplastic lymphoma kinase (ALK)-positive lung cancer or ROS1-positive lung cancer.

    <ul>
  • This research study involves three study drugs.
  • Lorlatinib
  • Binimetinib
  • Crizotinib
  • ul>

    tubal ligation
    ros1 gene rearrangement
    malabsorption
    malabsorption syndrome
    discomfort
    • 0 views
    • 16 Feb, 2024
    • 2 locations
    Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

    This research study involves the following investigational drugs:

    <ul>
  • Ipatasertib
  • Atezolizumab
  • ul>

    serum bilirubin level
    adjuvant therapy
    mastectomy
    breast surgery
    ipatasertib
    • 0 views
    • 16 Feb, 2024
    • 1 location
    Deep Brain Stimulation Surgery for Movement Disorders

    ul> Design <ul>

  • Researchers will screen patients with physical and neurological exams to decide whether they can have the surgery.
    • 0 views
    • 24 Nov, 2025