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Found 559 clinical trials
Antigen Presentation and Lymphocyte Response in Parkinson's Disease  

The way the immune system responds to certain PD-related proteins in PD donors compared to the way it responds in persons without or fewer PD related proteins is not well studied and this study aims to analyze the autoimmune response in each group. The study involves a one time visit …

bradykinesia
muscle rigidity
resting tremor
tremor
  • 1784 views
  • 16 Feb, 2024
  • 3 locations
Deep Brain Stimulation (DBS) for Parkinson's Disease International Study  

To gather data on DBS Therapy effectiveness in different geographic populations.

brain stimulation
dyskinesia
levodopa
  • 6 views
  • 16 Feb, 2024
  • 15 locations
Study on the Visual Condition in Parkinson's Disease  

Non motor symptoms and signs in Parkinson's disease (PD) also include a series of visual deficits; deepening these aspects could be useful for a better management of symptoms, to standardize a specific protocol for the issues related to vision and also to understand how these aspects are important for the …

motor symptoms
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Diagnosis of Parkinson s Disease by Means of Submandibular Gland Needle Biopsy

This study includes 35 PD patients who underwent submandibular gland needle biopsy. 25 neurologically healthy patients of the local otolaryngological clinic, in whom submandibular gland needle biopsy was performed due to a clinical indication, serve as controls.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Vigor and the LDR in Parkinson Disease Test  

Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine. The most effective treatment for PD is the drug levo-dopa, which partially replaces brain dopamine. Despite decades of successful use, how levo-dopa improves speed of movement in PD …

  • 0 views
  • 13 Nov, 2024
  • 2 locations
Neurodegenerative Diseases Registry

Due to the overlapping presentation and similar brain pathology, especially in the early stage of the diseases, it is difficult to differentiate idiopathic Parkinson's disease (iPD) from atypical parkinsonian syndromes, such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Similarly, distinguishing AD from other dementia syndromes including frontotemporal …

motor neuron disease
frontotemporal dementia
dementia with lewy bodies
brain pathology
supranuclear palsy
  • 0 views
  • 05 Aug, 2020
Biological Sample Collection for Research and Biobanking

The New York Stem Cell Foundation (NYSCF) is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells). NYSCF uses these samples to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, …

genetic testing
  • 0 views
  • 16 Feb, 2024
  • 1 location
Speech Linguistic and Acoustic Markers in Parkinson's Disease

We aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. We will administer various speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls. We will also explore the associations between genetic factors and speech and …

cognitive decline
mental deterioration
mild cognitive impairment
cognitive impairment
  • 0 views
  • 16 Feb, 2024
  • 1 location
Comparison of Outcomes in Asleep and Awake DBS With a Directional Electrode

To compare the clinical outcome of patients with Parkinson's disease (PD) treated with directional deep brain (dDBS) stimulation undergoing subthalamic deep brain stimulation operation (STN-DBS) under general anesthesia versus local anesthesia.

general anesthesia
brain stimulation
levodopa
tremor
dyskinesia
  • 0 views
  • 16 Feb, 2024
  • 1 location