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Found 559 clinical trials
Deep Brain Stimulation (DBS) for Parkinson's Disease International Study  

To gather data on DBS Therapy effectiveness in different geographic populations.

brain stimulation
levodopa
dyskinesia
  • 6 views
  • 16 Feb, 2024
  • 15 locations
Antigen Presentation and Lymphocyte Response in Parkinson's Disease  

The way the immune system responds to certain PD-related proteins in PD donors compared to the way it responds in persons without or fewer PD related proteins is not well studied and this study aims to analyze the autoimmune response in each group. The study involves a one time visit …

bradykinesia
tremor
resting tremor
muscle rigidity
  • 1784 views
  • 16 Feb, 2024
  • 3 locations
Diagnosis of Parkinson s Disease by Means of Submandibular Gland Needle Biopsy

This study includes 35 PD patients who underwent submandibular gland needle biopsy. 25 neurologically healthy patients of the local otolaryngological clinic, in whom submandibular gland needle biopsy was performed due to a clinical indication, serve as controls.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Attentional Performance in Parkinson Disease

Background Parkinson Disease (PD) is a nervous system disorder that affects movement. Dopamine is an important neurotransmitter in the brain. As PD progresses, there is less and less dopamine in the brain. Researchers think there may be a relationship between differences in attention and dopamine in people with PD. Objective …

motor symptoms
nervousness
MRI
nervous system disorder
attention deficit
  • 0 views
  • 16 Feb, 2024
  • 1 location
Quality-of-Life Index (Q-Index)

The main objective of this observational study is to use commonly-used connected objects (smartphones and smartwatches) to remotely assess and monitor the health-related quality of life (HrQoL) of people with Parkinson's disease at different stages of progression.

Accepts healthy volunteers
  • 0 views
  • 31 Jan, 2024
  • 9 locations
Neurodegenerative Diseases Registry

Due to the overlapping presentation and similar brain pathology, especially in the early stage of the diseases, it is difficult to differentiate idiopathic Parkinson's disease (iPD) from atypical parkinsonian syndromes, such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Similarly, distinguishing AD from other dementia syndromes including frontotemporal …

corticobasal degeneration
lewy body dementia
lewy body disease
dementia
neurodegenerative disorder
  • 0 views
  • 05 Aug, 2020
Biological Sample Collection for Research and Biobanking

The New York Stem Cell Foundation (NYSCF) is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells). NYSCF uses these samples to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, …

genetic testing
  • 0 views
  • 16 Feb, 2024
  • 1 location
Speech Linguistic and Acoustic Markers in Parkinson's Disease

We aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. We will administer various speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls. We will also explore the associations between genetic factors and speech and …

cognitive decline
mental deterioration
mild cognitive impairment
cognitive impairment
  • 0 views
  • 16 Feb, 2024
  • 1 location
Comparison of Outcomes in Asleep and Awake DBS With a Directional Electrode

To compare the clinical outcome of patients with Parkinson's disease (PD) treated with directional deep brain (dDBS) stimulation undergoing subthalamic deep brain stimulation operation (STN-DBS) under general anesthesia versus local anesthesia.

tremor
general anesthesia
dyskinesia
brain stimulation
levodopa
  • 0 views
  • 16 Feb, 2024
  • 1 location