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Found 1433 clinical trials
Vacuum Assisted Biopsy Immediately Before Surgery as an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer

Neoadjuvant chemotherapy (NAC) is common practice in the primary treatment of breast cancer, leading to a complete pathologic remission (pCR) of the tumor in more than 50% in aggressive tumor types. As NAC induces different response patterns, radiologic imaging is not sufficiently accurate in predicting residual disease. Because of this …

invasive breast cancer
residual tumor
HER2
immunostimulant
adjuvant chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 16 locations
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser

The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser

  • 0 views
  • 10 Jan, 2024
  • 1 location
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACTTest123)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

  • 0 views
  • 28 Mar, 2024
  • 9 locations
Tango for Alzheimer's Disease Patients' Caregivers

The goal of the project is to determine the extent to which indices of inflammatory biomarkers, cognition and mood, are influenced by a partnered, dance-based intervention vs control condition in African American (AA) female family caregivers, at high risk for Alzheimer's disease (AD).

alzheimer's disease
  • 24 views
  • 16 Feb, 2024
  • 1 location
Less Infections for the Diabetic Foot  

This is a randomized, unblinded, single-centre study. After eventual surgical debridement (not amputation), patients will be randomized to receive 1 of 2 targeted antibiotic regimens, in the ratio 1:1. For diabetic toe osteomyelitis, the patients will be randomized between a 3 and a 6 week's arm, for soft tissue infections …

antibiotic therapy
debridement
antibiotics
diabetic foot infection
osteomyelitis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Non-invasive Lipolysis on Human Thighs and Saddlebags

The study is a prospective two-arm, open-label, interventional study with four treatment procedures and two follow-up visits.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Lap-assisted vs. US-Guided Visualization of TAP Blocks

Peripheral nerve blocks have been effective in decreasing post-operative pain as well as the use of narcotics for numerous years. Typically, these blocks are placed by anesthesiologist via ultrasound. In more recent years, surgeons have been placing nerve blocks laparoscopically. Since there are few studies that looks compare the two …

narcotics
postoperative pain
nerve blocks
laparoscopic surgery
nerve block
  • 0 views
  • 16 Feb, 2024
  • 1 location
Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes

As of yet, the cause of Meniere's disease is uncertain and there is no cure. Given the lack of high level evidence for treatments, we seek to perform a randomized, placebo-controlled, double-blind, crossover, pilot trial of venlafaxine for treating Meniere's disease. Venlafaxine is a safe and well-tolerated medication. It has …

brain surgery
stroke
hyperlipidemia
hypertension
neurologic disorder
  • 0 views
  • 16 Feb, 2024
  • 1 location
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Patients eligible for this study have a type of blood cancer Acute Myeloid Leukemia (AML) which has come back or has not gone away after treatment. The body has different ways of fighting disease and infection, and this research study combines two different ways of fighting cancer with antibodies and …

hematologic malignancy
apheresis
leukemia
lymphoma
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Backpack Weight Impacts

Backpacking is an increasingly popular outdoor recreational activity. The base pack weight (BPW) includes gear that is not consumed or worn on the body: shelter, sleep system, weather-proofing layers and personal gear to ensure a degree of comfort and safety. As such, reducing BPW is one of the most important …

  • 0 views
  • 16 Feb, 2024
  • 1 location