Found 560 clinical trials
COPD-ICU Multicentre Prospective Observational Register (COPD-ICU)
This is a randomized, open-label, parallel group study to determine the optimal dose of CART-19 cells (of the two dose levels being assessed (1-5x10xE8 vs. 1-5x10xE7 CART-19 cells). This trial will be conducted in two stages. In Stage 2, the selected dose cohort will be expanded to enroll additional subjects, …
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- 21 Feb, 2023
scrumsecond sync
This is a randomized, open-label, parallel group study to determine the optimal dose of CART-19 cells (of the two dose levels being assessed (1-5x10xE8 vs. 1-5x10xE7 CART-19 cells). This trial will be conducted in two stages. In Stage 2, the selected dose cohort will be expanded to enroll additional subjects, …
- 0 views
- 22 Feb, 2023
- 1 location
PQ Test Trial ( Do not edit)
George's Respiratory Questionnaire (SGRQ) in former smokers with moderate-to-severe COPDEvaluate the safety and tolerability of itepekimab in former smokers with moderate-to-severe COPDEvaluate the pharmacokinetic (PK) profile of itepekimab in former smokers with moderate-to-severe COPDEvaluate immunogenicity to itepekimab in former smokers with moderate-to-severe COPDSecondary population (current smokers cohort)Estimate the efficacy of …
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- 01 Apr, 2024
- 4 locations
To Compare the Efficacy and Tolerability of A. Paniculata/A. Chilensis in Individuals With URTI
Paniculata and A.Chilensis are effective and safe in the treatment of typical cold-related symptoms in adults.
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- 08 Jul, 2021
Trial of Inhaled Anti-viral (SNG001) for SARS-CoV-2 (COVID-19) Infection
SNG001 is an inhaled formulation of interferon beta-1a it is currently in Phase II clinical trials for COPD patients. Synairgen has conducted randomised placebo controlled clinical trials of SNG001 involving >200 asthma and COPD patients.
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- 01 Feb, 2023
- 9 locations
Asthma
Asthma is a condition in which your airways narrow and swell and may produce extra mucus. This can make breathing difficult and trigger coughing, a whistling sound (wheezing) when you breathe out and shortness of breath. For some people, asthma is a minor nuisance. For others, it can be a …
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- 02 Jun, 2021
Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors
The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …
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- 16 Feb, 2024
- 1 location
A Study to Investigate Safety and Efficacy of iGlarLixi in Adult Patients With Type 2 Diabetes Mellitus
This is an intervention, phase IV, single-arm study to assess the safety and efficacy of iGlarLixi in adult patients with Type 2 diabetes.
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- 11 Mar, 2025
Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
To investigators' knowledge, this is the first study investigating effects of HFNC on sputum clearance in COPD patients. The purpose of the study is to determine the effects of HFNC on sputum clearance in acute exacerbation of COPD.
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- 16 Feb, 2024
- 1 location