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Found 518 clinical trials
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A Study of RC48-ADC(Antibody Drug Conjugate) and JS001 to Evaluate the Safety and Pharmacokinetics of Subjects With Locally Advanced or Metastatic Urothelial Cancer

This is an open-label, single-arm, Phase Ib/II investigator-initiated trial of RC48-ADC combined with JS001 to evaluate the safety and pharmacokinetics of subjects with locally advanced or metastatic urothelial cancer

metastatic urothelial carcinoma
adjuvant
ejection fraction
carcinoma
absolute neutrophil count
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  • 16 Feb, 2024
  • 1 location
Intravesical Gemcitabine and Docetaxel for BCG na ve Non-muscle Invasive Bladder Cancer

A single-arm, two-stage, open-label, phase 2 study investigating the safety and efficacy of intravesical gemcitabine/docetaxel for bacillus Calmette-Guerin (BCG)-nave patients with non-muscle invasive bladder cancer (NMIBC). All participants will receive an induction course of gemcitabine/docetaxel instillations followed by maintenance instillations if initial efficacy is seen. In addition to providing initial …

gemcitabine
combination therapy
carcinoma in situ
bacillus calmette-guerin
carcinoma
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  • 16 Feb, 2024
  • 1 location
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

nivolumab
carcinoma
advanced urothelial carcinoma
vegf
advanced renal cell carcinoma
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  • 05 Aug, 2020
A Prospective Multi-centre Single-blinded Study of UroCAD for Urothelial Carcinoma Diagnosis and Follow-up

Urothelial carcinoma (UC) is common malignancy and is considered to be one of the most expensive cancers. The traditional diagnostic methods of UC present with some shortcomings.

urine cytology
carcinoma
cystoscopy
cancer
transitional cell carcinoma
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  • 16 Feb, 2024
  • 1 location