Found 535 clinical trials
tDCS in Post-stroke Neglect Rehabilitation
Introduction Stroke is the main cause of disability in the world and its sequelae have a great impact in the functional independence and quality of life of patients and families. Unilateral spatial neglect is one of the most frequent cognitive deficits after stroke, and its maintenance is associated with poor …
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- 16 Feb, 2024
- 1 location
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Covid-19 patients surviving an admission to the ICU are expected to suffer from physical and cognitive impairments that will limit quality of life and return to pre-hospital level of functioning. In this present study, the investigators will evaluate the safety and feasibility of providing a novel clinical pathway combining ICU …
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- 16 Feb, 2024
- 1 location
Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients (tDCS) (tDCS)
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left dorsolateral prefrontal cortex (LDLPFC) will induce long-lasting effects in improving cognitive function and reducing cognitive fatigue and fatigability in PD patients.
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- 22 Jul, 2024
Tofacitinib for Immune Skin Conditions in Down Syndrome
People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug …
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- 16 Feb, 2024
- 1 location
Isoleucine Intake and Intermediary Metabolism in Type 2 Diabetes
The primary objective of this study is to determine the mechanism of reduced branched-chain amino acid (BCAA) oxidation to propionyl CoA and isoleucine intake can affect TCA cycle function in obese insulin resistant T2D. We will test the hypotheses that isoleucine and valine oxidation to propionyl CoA is reduced and …
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- 16 Feb, 2024
- 1 location
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad
Disturbed sleep is stressful to persons living with dementia (PLwD) and their caregivers. It contributes to earlier placement of the PLwD in nursing homes and increase the risk for many psychological and cognitive health issues and poor quality of life for both the PLwD and the caregivers. Given the potential …
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- 16 Feb, 2024
- 2 locations
Walking After Traumatic Brain Injury in Older Adults
The goal of this study is to test the effect of a planning, reminders, and micro-incentives intervention verses regular health education facts on physical activity participation over 12-weeks, in older adults who have previously suffered a non-penetrating mild or moderate TBI. Participants will provide information and be screened for eligibility …
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- 25 Jan, 2024
- 1 location
A Daily-Activity-Focused, Strategy-Based Educational Programme for Informal Dementia Carers
This study will assess the impact of the Dementia Carer Education Programme on the caregiving burden of informal dementia carers.Ninety informal dementia carers along with their care-recipients will be recruited and randomised to the experimental and control groups. All recruited dementia carers in the experimental group will receive the Dementia …
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- 16 Jun, 2025
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)
Interstitial lung diseases (ILD) are a highly incapacitating group of chronic respiratory diseases, leading to disabling symptoms and impaired capacity to perform activities of daily living and health-related quality of life (HRQoL). It is known that people with ILD are highly inactive and sedentary, and in a severe stage of …
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- 16 Feb, 2024
- 1 location
Integrative Therapy for Holistic Natural Cognition and Lifestyle Rehabilitation
An observational study to determine outcomes of older adults who are under naturopathic medical care for cognitive complaints at a specific clinic in Southern California.
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- 16 Feb, 2024
- 1 location