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Found 1430 clinical trials
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

total cavopulmonary connection
  • 0 views
  • 05 Aug, 2020
CPX-351 in Higher Risk Myelodysplastic Syndromes

Study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure

conjugated bilirubin
platelet transfusion
cardiovascular disease
central nervous system leukemia
leukemia
  • 0 views
  • 16 Feb, 2024
  • 12 locations
Low Dose Ruxolitinib in Combination With Methylprednisolone

This study is to determine the efficacy and safety of combined Low dose Ruxolitinib With Methylprednisone as Initial Therapy for the aGVHD(acute graft-versus-host disease )

tumorigenicity
blood disorder
hematologic disorders
acute graft versus host disease
methylprednisolone
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.

Patients who continue to be benefit after 6 cycles' treatment will receive additional cycles of treatment until progression of disease, unacceptable toxicity is observed or administrative discontinuation. (As long as it is proven safe).

myeloid leukemia
bone marrow procedure
acute leukemia
acute myeloid leukemia
leukemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Vestibular Nerve Stimulation to Improve Sleep

A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The purpose of this investigation device study is to collect data that will …

insomnia
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants

The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants.

radiopharmaceuticals
  • 0 views
  • 05 Aug, 2020
Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial

The purpose for this study is to determine whether left posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) is effective as ablation strategy for persistent atrial fibrillation (AF).

fibrillation
catheter ablation
atrial fibrillation
cardiac ablation
pulmonary vein isolation
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Sintilimab Combined With Apatinib and Capecitabine in Advanced Hepatocellular Carcinoma

This study aims to evaluate the efficacy and safety of Sintilimab (an Anti-PD-1 Inhibitor) combined with apatinib and capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma.

systemic chemotherapy
pd-1 inhibitor
thyroid stimulating hormone
neutrophil count
measurable disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Radiomics Tool for Pulmonary Nodule Risk Stratification

Final pulmonary nodule diagnosis will be categorized as malignant or benign. If the pathology report does not offer a specific pathologic diagnosis or is inconclusive (i.e., the biopsy was non-diagnostic), we will define pulmonary nodule resolution, shrinkage, or diameter stability at 12 months as a benign diagnosis.

  • 0 views
  • 11 Jul, 2024
  • 1 location
Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma

This study aims to collect convalescent plasma and use it as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit.

critical illness
shock
respiratory distress
acute respiratory distress
covid-19
  • 0 views
  • 05 Aug, 2020