Found 500 clinical trials
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects
Background The immune system defends the body against disease. It has many different parts spread out in the body, including in the blood and skin. To learn more about it, researchers want to study samples from people with healthy immune systems and people with conditions that affect how the immune …
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- 05 Aug, 2020
Gender Influence on Morbi-mortality in Pediatric Cardiac Surgery.
Recent studies show an important influence of gender on inflammatory reactions. Cardiac surgery is associated with a major systemic inflammatory response. The investigators want to evaluate the gender influence on morbi-mortality in pediatric cardiac surgery patients.
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- 16 Feb, 2024
- 1 location
Prospective Longitudinal Observational Research in Atopic Dermatitis
Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within …
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- 16 Feb, 2024
- 1 location
Evaluating the Role of Inflammation in Neonatal Epileptogenesis
The purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.
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- 16 Feb, 2024
- 4 locations
Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP)
Non-interventional, prospective, monocentric study on the exploration of leukocyte morphological parameters according to the infectious condition and response to corticosteroid therapy of septic patients.
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- 16 Feb, 2024
- 1 location
Follow-up of Critical COVID-19 Patients
The study will follow COVID-19 patients who required intensive care after 3-6 months and one year after discharge from the ICU with functional level as well as organ function to assess recovery after COVID-19. Blood and urine will be collected for biobanking.
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- 16 Feb, 2024
- 1 location
Cellular Immunity, Neuroendocrine, and Inflammatory Factors for Clinical Prognosis in Acute Coronary Syndrome
In acute coronary syndrome (ACS), there is an increase in cortisol levels, as an expression of the stress response, and C-reactive protein, as an expression of the inflammatory response, which are in turn associated with changes in the components of cellular immunity, and ultimately are predictors of clinical events.
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- 23 Jul, 2024
SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter Study
Recipients of kidney transplants make prolonged use of immunosuppressive drugs to inhibit the acquired immune response, notably the activity of lymphocytes. Due to this potential to modulate the immune and inflammatory response, it is speculated that the clinical and laboratory condition of COVID-19 in these patients is atypical. Preliminary evidence …
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- 16 Feb, 2024
- 1 location
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches
The hypotheses are that (I) the primary damage to the lung in SARS-CoV-2 ARDS is mediated through an exaggerated pro-inflammatory response causing primary endothelial dysfunction, and subsequently acting two-fold on the degradation of the lung parenchyma - through the primary cytokine response, and through recruitment of the inflammatory-monocyte-lymphocyte-neutrophil axis.
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- 16 Feb, 2024
- 1 location
Sequelae of Sars-CoV-2 Infections
By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the …
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- 16 Feb, 2024
- 1 location