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Found 504 clinical trials
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Optimizing the Treatment Strategy for Age-related Macular Degeneration

The purpose of this study is to compare two different treatment protocols for wet macular degeneration; the new protocol called "Observe and Plan" against the current standard protocol "Treat and Extend". Studies suggest that patients achieve equally good visual acuity with fewer controls and that they are more satisfied with …

treatment protocols
age-related macular degeneration
macular degeneration
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  • 05 Aug, 2020
  • 1 location
A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy (VERDANT)

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan. BI 771716 is being developed to treat people with geographic atrophy. Pegcetacoplan is a medicine …

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  • 11 Apr, 2025
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

atrophy
age-related macular degeneration
complement c5
geographic atrophy
maculopathy
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  • 16 Feb, 2024
  • 23 locations
A Study of NGM621 in Participants With Geographic Atrophy

This is a multi-center evaluation of NGM621 in a randomized, double-masked, sham-controlled study in participants with Geographic Atrophy secondary to Age-related Macular Degeneration.

atrophy
age-related macular degeneration
macular degeneration
maculopathy
  • 0 views
  • 05 Aug, 2020
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  • 07 Apr, 2025
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  • 07 Apr, 2025
  • 0 views
  • 11 Apr, 2025
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?

Research into the mechanisms of these conditions has proposed that some of their causes (e.g., macular degeneration/glaucoma and Alzheimer's disease) could be symptoms of an underlying common cause, or may be equally linked to a multifactorial context in frailty and aging.

deafness
macular degeneration
reading rehabilitation
glaucoma
alzheimer's disease
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  • 16 Feb, 2024
  • 2 locations