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Found 141 clinical trials
A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

This is a non-randomized Phase 2 study of sacituzumab govitecan (IMMU-132) in subjects with persistent or recurrent endometrial carcinoma.

x-rays
hormone therapy
formalin-fixed paraffin-embedded
sacituzumab govitecan
platinum-based chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma

This is a prospective single-arm study of endoscopic resection (ER) following concurrent chemoradiotherapy for stage I esophageal squamous cell carcinoma, to find if the treatment combination is useful by assessing its safety and efficacy.

squamous cell carcinoma of esophagus
chemoradiotherapy
bone metastases
squamous cell carcinoma
esophageal carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease the rate of disease progression and improve the survival outcome of patients with unresectable locally recurrent nasopharyngeal carcinoma compared with those treated with concurrent chemo-radiotherapy alone.

creatinine clearance rate
recurrent nasopharyngeal cancer
toripalimab
chemo-radiotherapy
nasopharyngeal carcinoma
  • 0 views
  • 05 Aug, 2020
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma

The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and efficacy in terms of biochemical control and survival, as well as of quality of life, …

lymphadenectomy
digital rectal examination
prostate carcinoma
adenocarcinoma of prostate
lymph node disease
  • 0 views
  • 16 Feb, 2024
  • 19 locations
A Study of Sintilimab Combined With Apatinib and Capecitabine in Advanced Hepatocellular Carcinoma

This study aims to evaluate the efficacy and safety of Sintilimab (an Anti-PD-1 Inhibitor) combined with apatinib and capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma.

neutrophil count
liver cancer
thyroid stimulating hormone
systemic chemotherapy
pd-1 inhibitor
  • 0 views
  • 16 Feb, 2024
  • 1 location
Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

In patients with locally advanced oral squamous cell carcinoma (OSCC), due to the large tumor burden and neck lymph node metastasis, comprehensive treatment is recommended, including surgery, radiotherapy, chemotherapy and others.

head and neck squamous cell carcinoma
chemoradiotherapy
tumor burden
camrelizumab
squamous cell carcinoma
  • 0 views
  • 05 Aug, 2020
Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma

A Phase II trial to study the effectiveness and security of cisplatin concurrent chemoradiotherapy plus TIL versus cisplatin concurrent chemoradiotherapy only in treating patients with FIGO stage IIIA to IVA cervical carcinoma.

chemoradiotherapy
cancer
squamous cell carcinoma
adenosquamous carcinoma
adenocarcinoma
  • 0 views
  • 05 Aug, 2020
Preliminary Antitumor Activity Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma

The primary objective of this study is to assess the preliminary antitumor activity as indicated by overall response rate (ORR) of tislelizumab in combination with lenvatinib in participants with unresectable locally advanced or metastatic hepatocellular carcinoma (HCC).

metastatic hepatocellular carcinoma
liver cancer
hepatocellular carcinoma
carcinoma
lenvatinib
  • 0 views
  • 05 Aug, 2020
A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

carcinoma
renal cell carcinoma
karnofsky performance status
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Bintrafusp Alfa in Previously Treated Patients With Recurrent and Metastatic (R/M) Non-keratinizing Nasopharyngeal Carcinoma (NPC)

This would be a phase II prospective single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of bintrafusp alfa in previously treated patients with recurrent and metastatic (R/M) non-keratinizing nasopharyngeal carcinoma (NPC).

neutrophil count
immunomodulators
platelet count
serum aspartate aminotransferase
adjuvant therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location