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Found 180 clinical trials
Postoperative Adjuvant Treatment of Completely Resected Mucosal Melanoma Phase II Study

A mucosal melanoma postoperative adjuvant treatment of multicenter, randomized, double-blind, placebo-controlled phase II study, evaluation of mucosal melanoma patients accept completely resected, Toripalima Combined with Temozolomide and Cisplatin postoperative adjuvant therapy efficacy and safety

immunostimulants
oral contraceptives
temozolomide
adjuvant therapy
mucosal melanoma
  • 0 views
  • 05 Aug, 2020
A Safety Tolerability and Efficacy of EIDD-2801 to Eliminate Infectious Virus Detection in Persons With COVID-19

This is a phase IIa, double-blind, placebo-controlled, randomized trial, designed to compare the safety, tolerability, and antiviral activity of EIDD-2801 versus placebo as measured by infectious virus detection in symptomatic adult outpatients with COVID-19

chills
cough
estrogen
follicle stimulating hormone
dyspnea
  • 0 views
  • 01 Feb, 2023
  • 1 location
Treatment With CSL312 in Adults With Coronavirus Disease 2019 (COVID 19)

This is a prospective, phase 2, multicenter, randomized, double blind, placebo controlled, parallel group study to assess the safety and efficacy of CSL312 administered intravenously, in combination with standard of care (SOC) treatment, in patients with Coronavirus disease 2019 (COVID 19)

coronavirus infection
pao2/fio2 ratio
fraction of inspired oxygen (fio2)
FIO2
administered intravenously
  • 0 views
  • 05 Aug, 2020
SCB-2019 as COVID-19 Vaccine

This is a randomized, double blind, placebo controlled, first-in-human (FIH) study to assess safety, reactogenicity, and immunogenicity of SCB-2019 at multiple dose levels, administered as 2 injections IM in healthy subjects.

electrocardiogram
bilateral oophorectomy
hysterectomy
serum pregnancy test
follicle stimulating hormone
  • 0 views
  • 05 Aug, 2020
Efficacy and Safety of Polyoxidonium in Hospitalized Patients With Coronavirus Disease COVID-19

The purpose of this study is to demonstrate the superiority of Polyoxidonium, lyophilizate for solution for injections and topical application, 6 mg over placebo in hospitalized patients with coronavirus disease (COVID-19). This is a multicentre prospective, randomized, double-blind, placebo-controlled, parallel-group phase IIb\IIIa clinical trial.

ct scan
coronavirus infection
SARS
chest x-ray
mechanical ventilation
  • 0 views
  • 16 Feb, 2024
  • 12 locations
A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia

This is a Phase II, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of MSTT1041A (astegolimab) or UTTR1147A in combination with standard of care (SOC) compared with matching placebo in combination with SOC in patients hospitalized with severe coronavirus disease 2019 (COVID-19) pneumonia.

pneumonia
coronavirus infection
chest x-ray
fraction of inspired oxygen (fio2)
capillary oxygen saturation
  • 0 views
  • 05 Aug, 2020
Tolerability Safety Pharmacokinetic Profile and Immunogenicity of a Recombinant Humanized Anti-SARS-CoV-2 Monoclonal Antibody (JS016) for Injection in Chinese Health Subjects

This is a randomized, double-blind, placebo-controlled, phase I clinical study to evaluate the tolerability, safety, pharmacokinetic profile and immunogenicity of JS016 (anti-SARS-CoV-2 monoclonal antibody) injection in Chinese healthy subjects after intravenous infusion of single dose.Eligible patients will be injection JS016 (anti-SARS-CoV-2 monoclonal antibody)

  • 0 views
  • 16 Feb, 2024
  • 1 location
A First in Human Study to Evaluate the Safety Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects

This is a first in human study of ETD002 a new drug being developed for the treatment of cystic fibrosis.The study is a randomised, double-blind, placebo-controlled, interventional study to assess the safety and tolerability of ascending single and repeat doses of inhaled ETD002 in healthy male and female subjects.

cystic fibrosis
  • 0 views
  • 05 Aug, 2020
Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer

This double blind, randomized phase II trial will investigate whether the addition of tocotrienol will improve the effect and lower the toxicity of standard chemotherapy and bevacizumab.

leucovorin
capecitabine
adenocarcinoma of the colon
oophorectomy
hormonal contraception
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Trial Assessing Temelimab Following Rituximab Treatment in Patients With Relapsing Forms of Multiple Sclerosis

Randomized, double-blind, placebo-controlled Phase IIa clinical study, assessing safety, tolerability, pharmacodynamic effects and pharmacokinetics of temelimab, administered at three different dose levels (18 mg/kg or 36 mg/kg or 54 mg/kg).

rituximab
multiple sclerosis
acquired immunodeficiency syndrome (aids)
  • 0 views
  • 16 Feb, 2024
  • 1 location