Found 134 clinical trials
Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas
The response analysis in CT or DWI-MRI and toxicity assessment will be performed after 6 weeks. In resectable tumors, a patient will be referred to surgery. In the case of unresectability, the patient will followed-up.
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- 16 Feb, 2024
- 1 location
Hyperpolarized Imaging for New Treatments
Inhalation of a hyperpolarized gas enables the visualization and quantification of regional ventilation in the lung and can be combined with structural MRI to assess both structure and function in parallel. The main Investigator and others have recently formed an international consortium (the 129Xe MRI Clinical Trial Consortium), comprised of …
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- 16 Feb, 2024
- 4 locations
CRPS - Diagnostics Pathophysiological Mechanisms and Response to Treatment With Noninvasive Brain Stimulation
The investigators study factors that may contribute to development, maintenance, or treatment responses with clinical, sleep, and psychiatric questionnaires and clinical examinations, quantitative sensory testing and neurophysiologic recordings, genetics, and MRI techniques.
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- 05 Aug, 2020
EBRT and HDR Brachytherapy for Unfavorable-intermediate High and Very High-risk Prostate Cancer
This study is trying to find out if the combination of Androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment (internal radiation implant procedure) and external beam radiation therapy (EBRT) treatments lead to less side effects.
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- 16 Feb, 2024
- 1 location
Self-Control in Bulimia Nervosa
Data will be collected using questionnaires and a technology called magnetic resonance imaging (MRI).
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- 05 Aug, 2020
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:
Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …
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- 16 Feb, 2024
- 1 location
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma
Patients with unequivocal recurrence (first or greater) established by MRI and meeting inclusion and exclusion criteria, will be eligible for OKN-007 treatment on this protocol.
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- 16 Feb, 2024
- 3 locations
Tissue K+ in Primary Hyperaldosteronism
Recent human studies found tissue sodium storage in patients with hyperaldosteronism that could be detected non-invasively by 23Na-MRI. Tissue sodium accumulation could be mobilized upon treatment of hyperaldosteronism. Besides, former animal studies applying chemical electrolyte analysis indicate that this aldosterone induced sodium storage might be accompanied by intracellular potassium loss.
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- 16 Feb, 2024
- 2 locations
Minocycline in MS: Confirmation of Benefit
Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging (MRI) with at least two brain T2 lesions which are at least 3 mm in diameter, and at least one of …
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- 16 Feb, 2024
- 1 location
Mental Effects of Analgesic Drugs: Paracetamol and Ibuprofen
The objective of the present study is to study paracetamol effects on social pain and empathy under standardized international conditions (ICH-GCP) for planning, conduction and reporting of clinical pharmaceutical studies in humans. The study included MRI imaging of brain activity, analysis of genomic biomarkers potentially explaining interindividual variation. It is …
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- 05 Aug, 2020