Found 515 clinical trials
tVNS in Long COVID-19
A prior open label study has shown that transcutaneous vagus nerve stimulation [tVNS] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill criteria for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). The purpose of this study is to compare …
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- 05 May, 2025
- 2 locations
Lu AF28996 in Patients With Parkinson's Disease (PD)
The purpose of this study is to investigate the safety of Lu AF28996, how well it is tolerated and what the body does to the drug in Patients With Parkinson's Disease
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- 16 Feb, 2024
- 1 location
Pharmacokinetic Evaluation and Local Tolerability of Dry Powder Amikacin Via the Cyclops
Main study parameters/endpoints: the following pharmacokinetic parameters: actual dose (dose minus remainder in inhaler after inhalation), AUC0-24 (area under the curve from 0-24 h), Cmax (maximum serum concentration), Tmax (time to maximum serum concentration). For the local tolerability the following procedures will be done, drop of FEV1 of >15 % …
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- 16 Feb, 2024
- 1 location
Time-restricted Eating in Cancer Survivorship: A Single-arm Feasibility Pilot Study
The investigators will assess the feasibility of delivering a time-restricted eating (TRE) intervention among cancer survivors with fatigue.
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- 16 Feb, 2024
- 1 location
ADME Study of Acoziborole in Healthy Subjects
This is a single centre, open-label, single group, non-randomised, single oral dose study in healthy male subjects designed to assess the mass balance recovery, PK, metabolite profile and metabolite identification, and exploratory pharmacodynamics of acoziborole. It is planned to enrol 6 subjects. All subjects will receive an oral dose of …
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- 16 Feb, 2024
- 1 location
Glasses for Adolescent Delayed Sleep-Wake Phase Disorder
The purpose of this study is to determine if evening amber glasses combined with stable wake times will show an increase in total sleep time (TST) and an advance in sleep onset times (shift earlier) compared to the control group.
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- 16 Feb, 2024
- 1 location
Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video
Genetic counseling and testing (GCT) provides invaluable information for women who are at-risk of hereditary breast and/or ovarian cancer (HBOC). Black women underutilize GCT compared to White women. This study will conduct a RCT to test the efficacy of a culturally-tailored theory-based video intervention aimed to address key psychosocial factors …
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- 16 Feb, 2024
- 1 location
Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma
The purpose of this research study is to investigate a shorter radiation treatment schedule for head and neck cancers in patients 70 years of age and older. Standard radiation treatment for head and neck patients normally requires that the patient travel to the hospital daily for 6-7 weeks to receive …
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- 16 Feb, 2024
- 4 locations
Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients
This study aimed to investigate the effect of low-dose (100 mg) asprin on the prevention of gastric cancer in the early gastric cancer patients with negative H. pylori status who underwent endoscopic submucosal dissection.
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- 16 Feb, 2024
- 9 locations
Safety and Efficacy of Samsung GEMS-H Device Training in Sub-Acute and Chronic Stroke
A single-site, interventional, single-arm trial to evaluate the safety and efficacy on functional mobility following Samsung GEMS-H (Gait Enhancing and Motivating System - Hip) device training in participants with sub-acute and chronic stroke.
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- 16 Feb, 2024
- 1 location