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Found 500 clinical trials
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Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

recurrent glioblastoma
gliadel
oral contraceptives
glioma
growth factor
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  • 16 Feb, 2024
  • 1 location
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

recurrent glioblastoma
glioblastoma multiforme
tumor treating fields therapy
renal function test
karnofsky performance status
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  • 16 Feb, 2024
  • 1 location
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help.

therapeutic agent
temodar
therapeutic agents
external beam radiotherapy
platelet count
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  • 16 Feb, 2024
  • 1 location