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Found 500 clinical trials
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Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

low grade glioma
dexamethasone
nitrosoureas
PCR test
tubal ligation
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  • 16 Feb, 2024
  • 1 location
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

glioblastoma
niraparib
MRI
recurrent glioblastoma
renal function
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  • 16 Feb, 2024
  • 1 location
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help.

blood tests
blood transfusion
absolute neutrophil count
gliosarcoma
cancer
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  • 16 Feb, 2024
  • 1 location