glioblastoma multiforme Clinical Research Trials

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Found 500 clinical trials

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Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Neurology
Recruiting

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

growth factor

monoclonal antibodies

absolute lymphocyte count

vascular endothelial growth factor

EGFR

0 views
16 Feb, 2024
1 location

Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Neurology
Recruiting

Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

renal function test

glioblastoma

niraparib

karnofsky performance status

glioblastoma multiforme

0 views
16 Feb, 2024
1 location

Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Neurology
Recruiting

Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help.

temodar

blood test

blood transfusion

selinexor

blood tests

0 views
16 Feb, 2024
1 location