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Found 534 clinical trials
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Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer

This double blind, randomized phase II trial will investigate whether the addition of tocotrienol will improve the effect and lower the toxicity of standard chemotherapy and bevacizumab. Half of the patients will receive tocotrienol and the other half placebo. Treatment is planned for a period of maximum six months and …

adenocarcinoma
serum bilirubin
fluorouracil
serum bilirubin level
bevacizumab
  • 0 views
  • 16 Feb, 2024
  • 1 location
Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer

The investigators hypothesize that intermittent first-line Panitumumab plus FOLFIRI is effective as the same regimen given continuously, in unresectable metastatic RAS and BRAF wild type colorectal cancer patients. Correlative studies on tumor and blood samples could identify potential biomarkers of efficacy and help defining personalized treatment strategy.

metastasis
adjuvant chemotherapy
adjuvant
BRAF
absolute neutrophil count
  • 0 views
  • 16 Feb, 2024
  • 1 location