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Found 1415 clinical trials
IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus

A recent randomized trial has proved the efficacy of Rituximab, a monoclonal anti-CD20 antibody against B-lymphocytes, as an efficacious therapy for pemphigus. Early use of rituximab was associated with better clinical outcomes, hence combination treatment of rituximab and intravenous immunoglobulins (IVIG) has shown to be effective for refractory pemphigus cases …

immunoglobulin g
corticosteroids
immunoglobulins
immunosuppressive agents
enzyme-linked immunosorbent assay
  • 0 views
  • 16 Feb, 2024
  • 1 location
Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension

This study is designed to investigate whether sympathoinhibition with moxonidine could provide added metabolic benefit compared to the second line therapy in the current guidelines.

amlodipine 5 mg
moxonidine
ace inhibitor
body mass index
amlodipine
  • 0 views
  • 16 Feb, 2024
  • 1 location
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies

This is a Phase I dose-finding study of FT596 as monotherapy and in combination with Rituximab or Obinutuzumab in subjects with relapsed/refractory B-cell Lymphoma or Chronic Lymphocytic Leukemia.

antibody therapy
b-cell lymphoma refractory
fludarabine
treatment regimen
obinutuzumab
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Carfilzomib Daratumumab Lenalidomide and Dexamethasone as First Line Treatment in Multiple Myeloma

Carfilzomib in combination with lenalidomide, daratumumab and dexamethasone (KRDd) can induce profound clinical responses. The investigators want to observe the effectiveness of the quadruple therapy of carfilzomib, lenalidomide, daratumumab and dexamethasone on patients receiving 8 cycles of KRDd with autologous stem cell transplantation versus patients with 8 cycles of KRDd …

daratumumab
bone lesion
multiple myeloma
calcium
autologous hematopoietic stem cell transplant
  • 0 views
  • 16 Feb, 2024
  • 1 location
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Introduction: Stroke continues to be one of the leading causes of disability in the Spanish adult population with the presentation of impairments such as alteration of mobility and a consequent reduction in quality of life. These sequelae, generally chronic, generates a significant expense and saturation of social and health services.

hemiplegia or hemiparesis
hemiparesis
physical rehabilitation
stroke
hemiplegia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study: Effects of a Collaborative Occupational Therapy Interactive Vaulting

Occupational therapy services will be integrated into an interactive vaulting program which is an equine assisted activity. Children with disabilities ages 5-17 will participate. The objectives of this study are to determine the influence of a collaborative occupational therapy interactive vaulting program on the executive function and social participation in …

developmental disabilities
  • 0 views
  • 05 Aug, 2020
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery

However, pain management in the post-operative period is critical to the ability to perform this procedure as an outpatient surgery. Traditionally, oral narcotic agents have been the preferred analgesic postoperatively in orthopaedic surgery.

oxycodone
analgesia
opioid use
analgesics
adjuvant
  • 0 views
  • 16 Feb, 2024
  • 1 location
Efficacy of rTMS and tDCS as Adjunctive Rehabilitation for Cerebrovascular Disease-related Gait Dysfunction

This study was a prospective, randomized, single-blind, parallel-controlled, multicenter clinical study to evaluate the efficacy and safety of repetitive transcranial magnetic stimulation and transcranial direct current stimulation assisted rehabilitation in the treatment of cerebrovascular disease-related gait disorders.

head mri
cerebrovascular disease
stroke
repetitive transcranial magnetic stimulation
lower limb
  • 0 views
  • 16 Feb, 2024
  • 6 locations
  • 0 views
  • 07 Oct, 2022
  • 4 locations
Brief Title: Study of BGB-10188 as Monotherapy and in Combination With Zanubrutinib and Tislelizumab

The purpose of this study is to determine the maximum tolerated dose (MTD), recommended Phase 2 dose(RP2D),safety & tolerability of BGB-10188: as monotherapy in participants with mature B-cell malignancies; oin combination with zanubrutinib in participants with relapse/refractory follicular lymphoma (R/R FL), mantle cell lymphoma (MCL) or diffuse large B-cell lymphoma …

renal cell carcinoma
breast cancer
tislelizumab
lung cancer
cancer, hepatocellular
  • 0 views
  • 16 Feb, 2024
  • 4 locations