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Found 471 clinical trials
Prospective Analysis of the Feasibility of the PASCAL Spacer Technology for Transcatheter Mitral Valve Repair in an All-comers Cohort

To identify changes on mitral valve morphology and functionality by the application of the PascalTM in MR.

mitral valve repair
  • 0 views
  • 16 Feb, 2024
  • 1 location
ASHCOM Shoulder System and Its Related Instruments

The objectives of this study are to confirm safety, performance and clinical benefits of the ASHCOM Shoulder System and its related instruments by analysis of standard scoring systems, radiographs and adverse event records.

total shoulder replacement
deficiency
  • 0 views
  • 16 Feb, 2024
  • 1 location
Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer

This is a long-term safety and efficacy study in subjects with CLN6 Batten disease who previously received a single intrathecal administration of AT-GTX-501.

gene therapy
ceroid lipofuscinosis
cln6
batten
neuronal ceroid lipofuscinosis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of COVID-19 on Platelet Aggregation

This is a mechanistic, observational, prospective, case and control study, to compare platelet aggregation, analyzed by Multiplate-ADP, in hospitalized patients diagnosed with COVID-19 versus healthy controls. Thus will be included 50 patients who present with respiratory symptoms within 72 hours of hospitalization and confirmation of the diagnosis of COVID-19 by …

SARS
acute respiratory syndrome (sars)
respiratory symptom
covid-19
chronic disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Different Susceptibility to SARS CoV-2 Infection Among Health Care Workers Highly Exposed to COVID-19.

The primary objective of this study is to establish differences in susceptibility to SARS CoV-2 infection among health care workers (HCW) highly exposed to patients with COVID-19 diagnosis. To ascertain this issue, we evaluated: Changes in receptor polymorphism (ACE2 and CD26 receptor study. SARS-CoV-2 CD4/CD8 T cell response (CTL) Different …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Oxalate and Urate Metabolism on CKD Evolution

The current study primarily aimed to characterize the oxalate and uric acid metabolism in CKD patients and to analyze its association with renal survival prognosis. Secondarily, the study is planned to determine whether hyperoxalemia and hyperuricemia are independent risk factors for cardiovascular events and mortality.

Uric Acid Test
antibiotics
hyperuricemia
chronic kidney disease, stage 1
chronic kidney disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Validation Study of WITHINGS BPM Core for the Detection of Atrial Fibrillation

The proposed clinical study aims to validate the diagnostic performance, compared to a reference ECG, of the electrocardiographic function of the BPM Core developed by Withings for the automatic identification of atrial fibrillation (AF).

fibrillation
atrial fibrillation
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Asthma: Phenotyping Exacerbations 2

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

maintenance therapy
skin prick
corticosteroids
prick skin
spirometry
  • 0 views
  • 16 Feb, 2024
  • 1 location
Asthma: Phenotyping EXacerbations

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

maintenance therapy
skin prick
corticosteroids
prick skin
spirometry
  • 0 views
  • 16 Feb, 2024
  • 1 location
Descriptive Study of the PSYchological Impact of CONFinement Measures in the General Population

Quarantine is an unpleasant experience : separation from loved ones, loss of freedom, uncertainty about infection status, boredom. It may lead to negative mental health consequences and thus the emergence of anxiety and depressive symptoms. From March 17th, 2020 to May 11th 2002, the French government has implemented national containment …

depressive symptoms
ebola virus disease
anxiety
covid-19
  • 0 views
  • 05 Aug, 2020