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Found 805 clinical trials
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

This study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene fusion.

direct bilirubin
ffpe
platelet count
gene fusion
solid neoplasm
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Trial to Evaluate AB011 Injection in Patients With CLDN18.2-positive Advanced Solid Tumors

This is an open, two-stage, phase I study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of AB011 injection in patients with CLDN18.2-positive advanced solid tumors.

treatment regimen
solid neoplasm
solid tumour
  • 0 views
  • 16 Feb, 2024
  • 1 location
NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

NBTXR3 is a drug that when activated by radiation therapy, may cause targeted destruction of cancer cells. Radiation therapy uses high energy to kill cancer cells and shrink tumors. Giving NBTXR3 followed by radiation therapy may work better to treat locally advanced or borderline-resectable pancreatic cancer compared to radiation therapy …

leucovorin
metastasis
celiac disease
platelet count
endoscopic ultrasound
  • 0 views
  • 16 Feb, 2024
  • 1 location
Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas

The response analysis in CT or DWI-MRI and toxicity assessment will be performed after 6 weeks. In resectable tumors, a patient will be referred to surgery. In the case of unresectability, the patient will followed-up.

hypofractionated radiation therapy
soft tissue sarcoma
hyperthermia
ct scan
radiation-induced cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Exercise and Diet Counseling Program in Improving Quality of Life in Stage I-III Breast Cancer Survivors

This trial studies the benefits of an exercise and diet counseling program in improving quality of life in stage I-III breast cancer survivors. Exercise and diet counseling may help improve weight loss and relevant clinical and patient-reported outcomes in overweight or obese breast cancer survivors.

anatomic stage iia breast cancer ajcc v8
stage ia breast cancer
stage i breast cancer
active treatment
stage iiic breast cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

Vaccines made from a gene-modified virus may help the body build an effective immune response to kill tumor cells.

glioma
recurrent disease
mpp2
immunohistochemistry
HIV Infection
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

The MIE with intrathoracic anastomosis (Ivor-Lewis) is increasingly used for the treatment of mid and lower esophageal cancers. Our study is trying to compare the safety, feasibility, and short-term and long- term outcomes between MIE Ivor-Lewis approach and MIE McKeown approach for the treatment of lower thoracic esophageal cancer and …

ivor
cancer
esophagus cancer
esophageal cancer
esophagectomy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Investigation of an Abdominal Compression Device

This study is applicable to patients undergoing lower lung or abdomen stereotactic ablative body radiotherapy (SABR) treatment. The purpose of the ACE 01 study is to identify if, the volume of healthy tissue within the treatment area and therefore subsequent side effects, can be reduced by using a commercially available …

adrenal
primary malignant neoplasm
lung cancer
cancer
epinephrine
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adenoid Cystic Carcinoma and Carbon Ion Only Irradiation

Adenoid cystic tumors are rare tumors of the head and neck region. Despite their slow growth, re-irradiation is often necessary due to the high metastatic risk.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Study of Hypofractionated Radiotherapy Alone in Locally Advanced Nonsmall Cell Lung Cancer Patients

The purpose of this research study is to find out what effects (good or bad) may come from a new way of doing radiation therapy for lung cancer. This study is for patients who are not able to get surgery or chemotherapy with their radiation. The way of doing radiation …

nonsmall cell lung cancer stage
pet/ct scan
mri brain
systemic therapy
hypofractionated radiation therapy
  • 0 views
  • 05 Aug, 2020