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Found 1430 clinical trials
Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video

Genetic counseling and testing (GCT) provides invaluable information for women who are at-risk of hereditary breast and/or ovarian cancer (HBOC). Black women underutilize GCT compared to White women. This study will conduct a RCT to test the efficacy of a culturally-tailored theory-based video intervention aimed to address key psychosocial factors …

genetic counseling
ovarian cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
High-Risk Veteran Initiative

Veterans at high-risk for hospitalization, including those with complex care needs, represent a large population of VHA patients who often do not receive evidence-based primary care practices that would help them avoid the hospital and improve their health. The high-RIsk VETerans (RIVET) Program will implement evidence-based practices that can support …

  • 0 views
  • 21 Sep, 2021
  • 3 locations
Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in Indonesia

The goal of this clinical trial is to determine the effectiveness of preventive therapy with diquafosol sodium 3% compared to sodium hyaluronate 0.1% to prevent dry eye disease in patient who will undergo cataract surgery. The main questions it aims to answer are: The percentage reduction in subjective symptoms and …

  • 0 views
  • 10 Jan, 2024
  • 1 location
Moxidectin for LF Cote d'Ivoire (DOLF)

The purpose of this study is to determine whether moxidectin (Mox) will be more effective than ivermectin (IVM) when used in single-dose combination therapies for lymphatic filariasis (LF).

antifilarial
combination therapy
ivermectin
moxidectin
filariasis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Venetoclax SL-401 and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

This phase II trial studies how well venetoclax, SL-401, and chemotherapy works in treating patients with blastic plasmacytoid dendritic cell neoplasm. Venetoclax may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. SL-401 is a recombinant protein consisting of IL-3 linked to a …

venetoclax
ara-c
hydroxyurea
blastic plasmacytoid dendritic cell neoplasm
treatment regimen
  • 0 views
  • 16 Feb, 2024
  • 1 location
Vitamin K Supplementation Study in Healthy Volunteers (Aim 2B)

The overall purpose of this study is to determine how variation in the CYP4F2 gene modulates the synthesis of vitamin K-dependent clotting factors. We propose that the CYP4F23 gene variant increases short- and long-term vitamin K concentrations in the liver by reducing the efficiency of vitamin K metabolism. The investigators …

  • 0 views
  • 05 Aug, 2020
A Novel Multi-factorial Criteria-based Rehabilitation Program for Chronic Mid-portion Achilles Tendinopathy

Sixty physically active patients (aged 18-45) with chronic mid-portion Achilles tendinopathy will be recruited to take part in the study. The patients will be diagnosed by a sports medicine doctor and an MRI scan and will be experiencing palpable Achilles pain at the time of inclusion. The patients will be …

tendinopathy
  • 0 views
  • 05 Aug, 2020
Consumer Perceptions of Milk Beverages

The objectives of this study are to: Investigate and describe perceptions of nutrient content, including calories, of plant-based milks and dairy milks without food labels (ie., no Ingredient or Nutrition Facts label) and how this impacts consumption choice. Determine understanding of nutrient content, including calories, of plant-based milks and dairy …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer

Detection of ovarian malignancy often occurs subsequent to the initial transvaginal sonography (TVS) screen therefore, it is important to offer continued screening to study participants based on our published algorithm. Screening will be available to participants for as long as they elect to receive it. The primary study endpoints are …

breast cancer
ovarian cancer
transvaginal ultrasound
hysterectomy
ovarian cancer screening
  • 0 views
  • 05 Aug, 2020
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

durvalumab
olaparib
carcinosarcoma
cancer
carboplatin paclitaxel
  • 0 views
  • 16 Feb, 2024
  • 95 locations