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Found 1830 clinical trials
Trial With the Treatment of Sertraline in Youth With Generalized Separation and/or Social Anxiety Disorders.

A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.

psychosis
oral contraceptives
evra
anxiety
separation
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Time-restricted Eating in Cancer Survivorship: A Single-arm Feasibility Pilot Study

The investigators will assess the feasibility of delivering a time-restricted eating (TRE) intervention among cancer survivors with fatigue.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluating Efficacy of the Dexmedetomidine Transdermal System for Postoperative Analgesia Following Abdominoplasty

The primary objective of this study is to evaluate the analgesic efficacy of Dexmedetomidine Transdermal System (DMTS), compared with placebo, in participants following abdominoplasty.

analgesia
analgesics
dexmedetomidine
postoperative pain relief
  • 0 views
  • 16 Feb, 2024
  • 4 locations
TTNS Versus Sham Therapy for Children With iOAB (TaPaS Part I)

Part I of the TaPaS trial forms part of a twofold clinical RCT: Part 1) A prospective RCT comparing the efficacy of transcutaneous tibial nerve stimulation (TTNS) with TTNS sham therapy for children with idiopathic overactive bladder on clinical and patient reported outcomes (PROMS). Part 2) A prospective RCT comparing …

sham therapy
incontinence
overactive bladder
percutaneous tibial nerve stimulation
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Trial to Evaluate the Potential Benefit of Adjuvant Chemotherapy for Small Bowel Adenocarcinoma

An open-label, randomised, controlled, multi-centre, trial with disease free survival as the primary end point. The worldwide collaboration is referred to as GLOBAL BALLAD and consists of a number of individual parallel prospective studies addressing the same objectives with similar designs brought together under the framework of the International Rare …

cancer
adenocarcinoma
metastasis
adjuvant chemotherapy
blood transfusion
  • 0 views
  • 16 Feb, 2024
  • 9 locations
Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients

This is an open label, single arm, multicenter, phase Ib study to evaluate the safety and clinical activity of the combination of ipatasertib, trastuzumab and pertuzumab in patients with unresectable locally advanced or metastatic HER2-positive breast cancer with tumors harboring PIK3CA mutations, candidates to receive maintenance HP after first line …

breast cancer
pertuzumab
platelet count
glycosylated hemoglobin
adenocarcinoma of the breast
  • 0 views
  • 16 Feb, 2024
  • 10 locations
A First-in-human Study to Assess the Safety Tolerability Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry.

This is a Phase 1 study to assess the the safety, tolerability and pharmacokinetics (PK) of AZD2373, following subcutaneous (SC) administration of single ascending doses (SAD) of AZD2373 in healthy male subjects of African ancestry.

body mass index
  • 0 views
  • 16 Feb, 2024
  • 1 location
DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)

This study will assess the safety, efficacy, and pharmacokinetics of DS-6157a in participants with advanced gastrointestinal stromal tumors (GIST).

ejection fraction
tyrosine
platelet count
cancer treatment
minor surgery
  • 0 views
  • 16 Feb, 2024
  • 2 locations
ESM-derived Personalised Feedback for Women at Risk of Depression

This study aims to examine the effectiveness of Experience Sampling Method (ESM) derived personalised feedback for women at risk of depressive disorder in Hong Kong, in reducing individuals depressive symptoms.

  • 0 views
  • 16 Feb, 2024
  • 1 location
From Addiction to Employment.

Patients with substance use disorders have low employment rates and are to a large extent on the outside of the ordinary labor market. Individual Placement and Support (IPS) is an evidence based method developed to aid persons with severe mental disorders in obtaining ordinary work. IPS has been used clinically …

substance use disorder
psychiatric disorder
addiction
mental disorders
substance use
  • 0 views
  • 16 Feb, 2024
  • 1 location