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Found 1695 clinical trials
Comparing the Efficacy and Safety of a New Additional Treatment With Tislelizumab in Non-Small Cell Lung Cancer (NSCLC)

The primary objective of this study is to evaluate and compare major pathological response(MPR) rate and event-free survival (EFS) in participants receiving tislelizumab plus platinum-based doublet chemotherapy as the new additional treatment followed by tislelizumab as adjuvant treatment versus participants receiving placebo plus platinum-based doublet chemotherapy as neoadjuvant treatment followed …

non-small cell lung cancer
measurable disease
adjuvant
lung cancer
immunomodulators
  • 0 views
  • 16 Feb, 2024
  • 41 locations
A Study to Evaluate Enfortumab Vedotin in Subjects With Previously Treated Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

The primary purpose of this study is to determine the antitumor activity of enfortumab vedotin as measured by confirmed objective response rate (ORR). This study will also assess other measures of antitumor activity; overall survival (OS); as well as the safety and tolerability of enfortumab vedotin.

  • 0 views
  • 16 Feb, 2024
  • 8 locations
Lap-assisted vs. US-Guided Visualization of TAP Blocks

Since there are few studies that looks compare the two techniques we aim to perform a randomized control trial to demonstrate if a laparoscopic placed nerve block is as efficient and accurate as an ultrasound placed block.

peripheral nerve block
nerve blocks
laparoscopic surgery
narcotics
nerve block
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

Patients will be treated with the combination of copanlisib and rucaparib for as long as the patient does not have clinically significant progressive disease and/or unacceptable toxicity and/or as long as the investigator deems that the patient is benefiting from treatment.

psa level
glycosylated hemoglobin
liver metastasis
lipase
metastatic prostate cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Ethics Communication in Groups Among Healthcare Professionals (The Ethics-com Study). (Ethics-com)  

Moral distress has been described as a condition with frustration, guilt, anger and as one reason for health care professionals to leave the profession. Ethics communication in groups has been showed to work as support for health care professionals in ethically difficult situations and further work as a tool to …

Accepts healthy volunteers
  • 0 views
  • 22 Feb, 2022
  • 2 locations
Effect of 1 25-dihydroxyvitamin D3 Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons

The aim of this study is to assess the effects of 1,25(OH)2D3 on insulin secretion by the pancreas and glucose utilization by skeletal muscle as well as to determine the effects of 1,25(OH)2D3 on muscle strength in pre-diabetic persons

fasting
body mass index
serum glucose
prediabetic state
insulin
  • 0 views
  • 16 Feb, 2024
  • 1 location
Glycogen Metabolism in Children

This study aims to analyze the glycogen metabolism before and after an overnight sleep as well as after a breakfast in children between 8 and 12 years old.

health screening
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Compare the Pharmacokinetics of BR4002 and BR4002-1 in Healthy Volunteers

This study is designed as a randomized, open-label, single-dose, 6x3 crossover study.

chronic disease
body mass index
electrocardiogram
electrocardiogram (ecg)
  • 0 views
  • 16 Feb, 2024
  • 1 location
Battlefield Acupuncture for Pain in Hidradenitis Suppurativa

The investigators will investigate battlefield acupuncture as a treatment for the pain of hidradenitis suppurativa.

treatment regimen
hidradenitis
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Efficacy and Safety of a Latest Dural Substitute

Surgeons also provided data on the ease of use of the dural sealing techniques, as well as preparation and application times. The above-mentioned date were used to evaluate the efficacy and safety of Lyoplant Onlay .

  • 0 views
  • 16 Feb, 2024
  • 1 location