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Found 93 clinical trials
Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate …

bisphosphonate therapy
inflammatory breast cancer
HER2
targeted therapy
primary lesion
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Study of DC-CIK Cells as a Post-remission Treatment for Malignant Tumors

Screening stage Evaluation of disease Grouping of patients Infusion of cells Surveillance of adverse effect

malignant solid neoplasm
hair thinning
decitabine
cancer treatment
malignant solid tumor
  • 0 views
  • 16 Feb, 2024
  • 1 location
Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

The retrospective data of our center showed that the sequential radiochemotherapy of "chemotherapy-radiotherapy-chemotherapy" in the "sanwich" mode could improve the survival outcome in patients with advanced endometrial cancer. A multicenter, prospective, randomized controlled study to compare the "sanwich" mode of radiochemotherapy and the "concurrent chemoradiotherapy followed by chemotherapy" mode will …

hysterectomy
carcinoma
adjuvant radiotherapy
endometrial cancer
cancer
  • 0 views
  • 05 Aug, 2020
Postoperative Radiotherapy in Breast Cancer- Concurrent or Sequential With Chemotherapy (CONCERT)

This clinical research aims to determine if concurrent chemotherapy and radiation therapy is more effective than sequential chemotherapy and radiation therapy for patients with stage IIB-III breast cancer. It seeks to answer the following key questions:When compared to sequential treatment, does concurrent chemoradiotherapy increase disease-free survival?What effects does concurrent treatment …

  • 0 views
  • 02 May, 2025
Reduced vs Conventional Dosage Intensity-modulated Radiotherapy for Chemotherapy-sensitive Stage II-III Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that radiotherapy with reduced dose could significantly reduce the incidence of radiotherapy toxicities, improve the quality of life of patients while ensuring the tumor control rates for NPC patients staged as II-III who are sensitive to induction chemotherapy (imaging evaluation …

intensity-modulated radiotherapy
carcinoma
creatinine clearance rate
intensity-modulated radiation therapy
karnofsky performance status
  • 6 views
  • 16 Feb, 2024
  • 6 locations
Stress Management and Biological Age in Breast Cancer Patients.RCT  

Intense stress has harmful effects on the body, contributing to various disorders. Breast cancer patients experience a build-up of stress due to their diagnosis and treatments. Stress can cause epigenetic changes in a cellular level (such as accelerated increase in biological age) that may negatively affect oncological treatments. This study …

  • 0 views
  • 03 Oct, 2023
  • 13 locations
Test-Trial-29-Aug  

Intense stress has harmful effects on the body, contributing to various disorders. Breast cancer patients experience a build-up of stress due to their diagnosis and treatments. Stress can cause epigenetic changes in a cellular level (such as accelerated increase in biological age) that may negatively affect oncological treatments.This study aims …

  • 0 views
  • 08 Sep, 2023
  • 1 location
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

carcinoma
EGFR
cisplatin
renal function test
nimotuzumab
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adaptative MR-Guided Stereotactic Body Radiotherapy of Liver Tumors

More, this accelerator allows a re-optimization of the initial dosimetric plan to the anatomical changes of the day to allow an MRI guided adaptive radiotherapy.

hepatitis
stereotactic radiation therapy
skin cancer
chelates
metastasis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas

After a screening, which consists of biopsy, physical examination, initial diffusion-weighted magnetic resonance imaging (DWI-MRI) or body computed tomography (CT) scan, blood tests and case analysis on Multidisciplinary Team (MDT) meeting, a patient with radiation-induced or in-field recurrent sarcoma will receive the hypofractionated radiotherapy with deep hyperthermia (twice a week) …

soft tissue sarcoma
hyperthermia
sarcoma
radiation-induced cancer
fever
  • 0 views
  • 16 Feb, 2024
  • 1 location