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Found 38 clinical trials
Antigen Presentation and Lymphocyte Response in Parkinson's Disease  

The way the immune system responds to certain PD-related proteins in PD donors compared to the way it responds in persons without or fewer PD related proteins is not well studied and this study aims to analyze the autoimmune response in each group. The study involves a one time visit …

muscle rigidity
bradykinesia
tremor
resting tremor
  • 1784 views
  • 16 Feb, 2024
  • 3 locations
Diagnosis of Parkinson s Disease by Means of Submandibular Gland Needle Biopsy

This study includes 35 PD patients who underwent submandibular gland needle biopsy. 25 neurologically healthy patients of the local otolaryngological clinic, in whom submandibular gland needle biopsy was performed due to a clinical indication, serve as controls.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Deep Brain Stimulation (DBS) for Parkinson's Disease International Study  

To gather data on DBS Therapy effectiveness in different geographic populations.

dyskinesia
levodopa
brain stimulation
  • 6 views
  • 16 Feb, 2024
  • 15 locations
Attentional Performance in Parkinson Disease

Background Parkinson Disease (PD) is a nervous system disorder that affects movement. Dopamine is an important neurotransmitter in the brain. As PD progresses, there is less and less dopamine in the brain.

parkinsonism
nervousness
neurologic findings
nervous system disorder
attention deficit
  • 0 views
  • 16 Feb, 2024
  • 1 location
Quality-of-Life Index (Q-Index)

The main objective of this observational study is to use commonly-used connected objects (smartphones and smartwatches) to remotely assess and monitor the health-related quality of life (HrQoL) of people with Parkinson's disease at different stages of progression.

Accepts healthy volunteers
  • 0 views
  • 31 Jan, 2024
  • 9 locations
Speech Linguistic and Acoustic Markers in Parkinson's Disease

We aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. We will administer various speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls.

cognitive decline
mental deterioration
mild cognitive impairment
cognitive impairment
  • 0 views
  • 16 Feb, 2024
  • 1 location
Comparison of Outcomes in Asleep and Awake DBS With a Directional Electrode

To compare the clinical outcome of patients with Parkinson's disease (PD) treated with directional deep brain (dDBS) stimulation undergoing subthalamic deep brain stimulation operation (STN-DBS) under general anesthesia versus local anesthesia.

dyskinesia
general anesthesia
brain stimulation
levodopa
tremor
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Novel Machine Learning Algorithm to Predict the Lewy Body Dementias

Parkinson's disease dementia (PDD) and Dementia with lewy bodies (DLB) are dementia syndromes that overlap in many clinical features, making their diagnosis difficult in clinical practice, particularly in advanced stages.

movement disorder
dementia
lewy body disease
  • 0 views
  • 16 Feb, 2024
  • 1 location