Found 370 clinical trials
Ultra - Brief Crisis IPT-A Based Intervention for Suicidal Children and Adolescents (IPT-A-SCI)
The current adaptation of IPT-A is comprised of five weekly sessions, followed by monthly follow-up caring email contacts to the patients and their parents, over a period of three months.
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- 16 Feb, 2024
- 1 location
Safety Tolerability and Immunogenicinity of a Coronavirus-Like Particle COVID-19 Vaccine in Adults Aged 18-55 Years.
The same process will be followed for the second vaccine administration. All subjects will be followed for a period of six months after the second administration of the vaccine for safety and immunogenicity testing at the end of the follow-up period.
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- 01 Feb, 2023
- 2 locations
Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia
The study consists of a 6 month randomized, double blind, placebo-controlled period, followed by 1 year of treatment with crinecerfont. Duration of participation is approximately 20 months.
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- 16 Feb, 2024
- 1 location
Effect of HF rTMS on Serum BDNF in Cocaine Use Disorder
Additionally, a comparative group (without rTMS intervention) will be included to equivalently measure described variables during periods without cocaine consumption.
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- 01 Apr, 2024
- 1 location
Evaluation of a New Supporting Ostomy Product
It is the expectation that median wear time is slightly reduced in the period when subjects are using the supporting product with their ostomy appliance. Long-term benefits of the test product may be less skin redness, less worry of leakage and/or improvement in quality of life and social activities.
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- 16 Feb, 2024
- 1 location
Neoadjuvant Endocrine Therapy Tolerance in Geriatric Early Stage ER+ Breast Cancer
Tolerance of the endocrine therapy will be assessed by patient reported outcome (PRO) measures during neoadjuvant and adjuvant endocrine therapy treatment periods. Breast cancer participants and their surgical oncologists will be asked their preference regarding radiation therapy before starting endocrine therapy and again post-operatively.
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- 16 Feb, 2024
- 1 location
Comparison of Virtual Reality to Tablet-based Distraction in Children
Other comparison measures will include preoperative parent/caregiver anxiety, anesthesia mask acceptance characteristics at the time of induction, and time to fully recover in the post-operative period.
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- 16 Feb, 2024
- 1 location
Happy Hands Pilot Study
Patient-reported outcomes and grip strength will be collected before and after the 12 week intervention period. Change in pain, stiffness, grip strength, disease activity and quality indicators will be assessed after 12 weeks.
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- 09 Dec, 2021
- 2 locations
Teaching Novel Values-Based Skills to Improve Long-Term Weight Loss
This NIDDK funded R01 project is a randomized controlled clinical trial to compare the efficacy of an intervention based on Acceptance and Commitment Therapy (ACT) and a Self-Regulation (SR) intervention on weight loss maintenance over a 30-month period. All participants will first complete a well-validated online weight loss intervention (months …
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- 16 Feb, 2024
- 1 location
Nivolumab in Combination With Temozolomide and Radiotherapy in Children and Adolescents With Newly Diagnosed High-grade Glioma
This phase will start when the RP2D has been defined after the last patients evaluable for DLT achieved the first 6 weeks of treatment (the radio-chemotherapy period) with a DLT rate below 30% during the the phase I study.
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- 16 Feb, 2024
- 1 location