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Found 66 clinical trials
First-in-Human Dose Escalation Trial of ATRC-101 in Adults With Advanced Solid Malignancies

ATRC-101-A01 is a first-in-human, Phase 1b, open-label trial to characterize the safety, tolerability, pharmacokinetics (PK), and biological activity of escalating doses of ATRC-101, an engineered, fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally-occurring human antibody.

measurable disease
non-small cell lung cancer
cancer therapy
growth factor
blood transfusion
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adaptative MR-Guided Stereotactic Body Radiotherapy of Liver Tumors

Hepatic metastases are common in solid cancers (up to 30% of patients with colorectal cancer and up to 50% of patients during their follow-up). The incidence of primary liver cancer increases due to the increase in chronic liver diseases induced by excessive alcohol consumption, hepatitis B and C viruses, and …

liver cancer
hepatitis
stereotactic radiation therapy
chelates
skin cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers RT-CAMSS Study

This trial tests new methods and materials for the real-time chemotherapy-associated side effects monitoring support system (RT-CAMSS) in patients with gastrointestinal cancers undergoing chemotherapy. RT-CAMSS is a monitoring support system that provides patients with evidence-based information and side-effect management and coping skills, emotional support and validation, and proactive care via …

stage iiic colorectal cancer ajcc v8
stage iva colorectal cancer ajcc v8
stage iv colorectal cancer ajcc v8
stage iv colorectal cancer
folfox regimen
  • 0 views
  • 16 Feb, 2024
  • 1 location
Long-term Consumption of Resistant Starch Type-4 (RS4)

The primary objective of the current proposal is to determine the effectiveness of long-term consumption of Fibersym RW for improving blood lipids (including cholesterol) and body composition. The overall goal of this clinical research is to determine the potential effects that RS4 consumption may have on the prevention of obesity …

blood lipids
LDL Cholesterol
cholesterol measurement
  • 0 views
  • 16 Feb, 2024
  • 1 location
An Adaptive Dyadic Self-directed Coping and Self-management Skills Training Intervention for Caregivers of Individuals With Cancer

High-quality cancer care in Canada relies on family caregivers. Since cancer treatment is provided more and more in outpatient clinics, family caregivers now provide most of the support and care patients need when they return home. The problem is that caregivers often do not feel they have the knowledge and …

hormone therapy
chat
anxiety
motivational interviewing
cancer therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal Cancer

Colorectal cancer is the third most frequent neoplasm after prostate and lung in man and breast and lung cancers in woman from Western Countries.

aflibercept
metastatic colorectal cancer
bevacizumab
growth factor
colorectal cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Patients' Guidance With Onco-Coaching and CANKADO on Systemic Chemotherapy for Metastatic Colorectal Cancer

This is a prospective, single arm, non-interventional project to evaluate the benefit/influence of individualized patient education and guidance with a web-based e-Health platform called CANKADO on patient reported outcomes (PRO) for patients with metastatic colorectal cancer. The focus will be on patient reported outcomes (PRO), distress, Quality of Life (QoL), …

metastatic colorectal cancer
cancer
colorectal cancer
systemic chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 2 locations
The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.

The role of gut microbiota in anastomosis insufficiency in patients operated for colorectal cancer and for peritoneal carcinomatosis is going to be investigated. This is a pilot study.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Establishment of Squamous Cell Organoids of the Head and Neck to Assess Their Response to Innovative Therapies

These characteristics therefore allow them to summarize the clinical spectra of cancers, but also to be models for studying tumor progression as has been done with organoids for colorectal cancer. They are also very close morphologically and genetically to the tumor from which they derive.Finally, clinical trials are underway to …

tumor progression
mouth cancer
squamous cell carcinoma of the oral cavity
basal cell carcinomas
squamous cell carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Which Type of Laparoscopic Colectomy Right or Left Have Better Postoperative Outcomes for the Patients?

Laparoscopic surgery decreased the morbidity of colorectal surgery. The two most common surgeries for colorectal cancer are right and left colectomy. Objective: To compare perioperative morbidity of the right versus left colectomy for cancer, as well as the quality of laparoscopic oncologic resection of both procedures.

  • 0 views
  • 05 Aug, 2020