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Found 1415 clinical trials
Topotecan Episcleral Plaque for Treatment of Retinoblastoma

This single site, single-arm, non-randomized, dose escalation phase I toxicity clinical trial will assess primarily the safety and secondarily the efficacy of episcleral topotecan in patients with active residual or recurrent intraocular retinoblastoma in at least one eye following completion of first-line therapy.

topotecan
brachytherapy
renal function
platelet count
intraocular retinoblastoma
  • 0 views
  • 05 Aug, 2020
Glasses for Adolescent Delayed Sleep-Wake Phase Disorder

The purpose of this study is to determine if evening amber glasses combined with stable wake times will show an increase in total sleep time (TST) and an advance in sleep onset times (shift earlier) compared to the control group.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Digestion of Gluten in the Presence of Enzymes

This study evaluates the impact of two dietary supplements (Glutalytic and DE111) and of oatmeal properties on the digestion of gluten and starch and on the glycemic response.

  • 0 views
  • 05 Aug, 2020
A Study to Evaluate the Safety Tolerability Pharmacokinetics Pharmacodynamics Bioavailability and Food-effects of EA1080 in Healthy Caucasian and Japanese Male Participants

The primary purpose of the study is to evaluate the safety and tolerability of EA1080 following single and multiple oral doses in healthy Caucasian and Japanese male participants.

body mass index
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Trial of Traffic Light Labeling With Behavioral Nudges and a Healthy Recipe Database to Increase Selection of Healthier Foods in Client-choice Food Pantries

This study is a pilot evaluation of the Healthy Pantry Program, a new behavioral economics-based training that allows pantry staff to learn how to implement nudges integrating traffic-light nutrition labeling and a healthy recipe database in the pantry environment. The hypothesis is that participation the Healthy Pantry Program will lead …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Multi-4SCAR-T Therapy Targeting Breast Cancer

The purpose of this study is to assess the feasibility, safety and efficacy of multiple 4th generation CAR-T cells targeting Her2, GD2, and CD44v6 surface antigen in breast cancer. Another goal of the study is to learn more about the activities of the multi-CAR T cells and their persistency in …

immunosuppressive agents
neutrophil count
immunosuppression
serum bilirubin
  • 2 views
  • 05 Aug, 2020
Hypofractionation And Ultra-Hypofractionation In Adjuvant Radiotherapy For Breast Cancer

Prospective randomized study comparing 5 fractions in alternative days to standard 15 fractions regarding effectiveness and feasibility during adjuvant treatment in breast caner patients aged above 50 years

stage iv breast cancer
hypofractionated radiation therapy
immunomodulators
immunostimulant
ct scan chest
  • 0 views
  • 16 Feb, 2024
  • 1 location
Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness

The primary aim of this study is to examine the efficacy of a one-session, hour-long HIPAA-compliant video platform-based mindfulness + compassion telehealth intervention on reducing feelings of loneliness during COVID-19 quarantine. Participants (n=120) currently isolating due to COVID-19 will be randomized to one of three interventions: (a) mindfulness + compassion …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Action Observation Therapy With Otago Exercises on Balance and Quality of Life in Older Adults  

This study is to determine to see the effect of action observation therapy with otago exercise on Balance and Quality Of Life.

Accepts healthy volunteers
  • 0 views
  • 01 Sep, 2023
  • 18 locations
Which Factors Influence the Outcome After Anatomical and Reverse Shoulder Arthroplasty?

The aim of this study is to investigate pre-, intra- and post-operative factors that influence post-operative outcome (shoulder pain, shoulder function and quality of life) after shoulder arthroplasty.

  • 0 views
  • 16 Feb, 2024
  • 1 location