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Found 1815 clinical trials
Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

Patients with refractory and/or recurrent solid tumor have poor prognosis despite complex multimodel therapy and therefore, novel approaches are urgently needed. This study attempts to treat these diseases using T cells genetically modified with a 4th generation lentiviral chimeric antigen receptor (4SCAR fused with an inducible apoptotic caspase 9 domain) …

serum bilirubin
tyrosine
growth factor
solid tumor
solid neoplasm
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Comparative Effects of Perturbation and Functional Stabilization Training on Patellofemoral Pain Syndrome

The main objective of this study is to determine the comparative effects of perturbation and functional stabilization training on pain, balance, and performance in athletes with patellofemoral pain syndrome(PFPS). Patellofemoral pain syndrome is one of the well known causes of anterior knee joint pain. Proximal and distal joint muscle imbalances …

Accepts healthy volunteers
  • 0 views
  • 22 Jul, 2024
403 trial & test1

The research study is being done to understand both why and how scleroderma and related female-biased diseases affect women and men differently.  Though we do not know what causes these diseases, we do know that women are much more likely to develop them than men.  We are studying how the …

  • 0 views
  • 28 Apr, 2025
Outcome of Facial Palsy Following Rehabilitation

Retrospective case series,the aim of this study is to assess the outcome and rate of complications in patients with facial palsy following rehabilitation, a retrospective study.

bell's palsy
peripheral facial palsy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluating Efficacy of the Dexmedetomidine Transdermal System for Postoperative Analgesia Following Abdominoplasty

The primary objective of this study is to evaluate the analgesic efficacy of Dexmedetomidine Transdermal System (DMTS), compared with placebo, in participants following abdominoplasty.

postoperative pain relief
dexmedetomidine
analgesics
analgesia
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Multicenter Perspective Study: Clinical Evaluation of the Persona MC With Preservation or Sacrifice of the PCL

Prospective, multicenter study on the Total Knee Prosthesis available on the market "Persona Medial Congruent knee". Primary endpoint -Evaluation of the survival of the implant after 5 years of follow-up Secondary endpoints Evaluation of the survival of the implant at 10 years of follow up. Evaluation of clinical and radiographic …

knee arthroplasty
knee pain
arthritis
polyarthritis
patellectomy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Nivolumab Ipilimumab and Chemoradiation in Treating Patients With Locally Advanced Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) remains a dreadful disease due to its often advanced stage at diagnosis and poor sensitivity to chemotherapy. A locally unresectable tumor (locally advanced pancreatic cancer (LAPC)) is present in 30% of the cases and is defined as a surgically unresectable tumor encasing the adjacent arteries [celiac …

teratogenicity
cancer
platelet count
pancreatic cancer
celiac disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Music as Analgesia During Neonatal Circumcision

Neonatal circumcision is one of the most frequently performed and more painful procedures. Sharara et al (2017) showed the combination of EMLA + Sucrose + Ring Block provides the highest standard of pain management. A combination which has been adopted by practitioners who perform circumcisions at the normal nursery at …

emla
analgesia
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Effect of High Protein and Early Resistance Exercise Versus Usual Care in Critically Ill Patients (EFFORT-X Trial)

This is a 2-arm, parallel-group, randomized controlled trial that investigates the effect of combined high protein and early resistance exercise versus usual care on muscle mass, quality and strength, clinical outcomes, functional outcomes and quality of life in mechanically ventilated critically ill patients

  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Nervous System Mobilization on Athletes' Performance

This study aims to compare the effects of two diferente doses of nervous system mobilization on athletes performance.

nervousness
nervous system
  • 0 views
  • 16 Feb, 2024
  • 1 location