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Found 36780 clinical trials
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

The overall aim of this study will be to collect tumour biopsies, biomarkers present in the blood, and other biological specimens which can be used to try to understand why resistance to anti-cancer treatment occurs, and to develop predictive biomarkers of this resistance in patients with locally advanced and metastatic …

blood test
advanced melanoma
cancer
cancer treatment
metastatic malignant melanoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cerebral Morbidity After Radiation Therapy for Brain Tumors

All types of brain tumours apart from glioblastoma will be included.

brain tumor
meningioma
pituitary
glioblastoma multiforme
medulloblastoma
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Impact of the Comprehensive Geriatric Assessment on the Quality of Life OF Elderly Patients

Impact of the Comprehensive Geriatric Assessment on the Quality of Life of elderly onco-hematologic patients' candidates for complex antitumoral therapies: clinical and biological correlatives

cancer
hematologic malignancy
  • 0 views
  • 05 Aug, 2020
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years.

blood test
neuron-specific enolase
fasting
vasoactive intestinal polypeptide
pancreatic polypeptide
  • 0 views
  • 05 Aug, 2020
RadioPathomics Artificial Intelligence Model to Predict Tumor Regression Grading in Locally Advanced Rectal Cancer

In this study, investigators apply a radiopathomics artificial intelligence (AI) supportive model to predict neoadjuvant chemoradiotherapy (nCRT) response before the nCRT is delivered for the patients with locally advanced rectal cancer (LARC). The radiopathomics AI system predicts individual tumor regression grading (TRG) category based on each patient's radiopathomics features extracted …

MRI
rectal cancer
metastasis
fluorouracil
adjuvant therapy
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer Patients

Current guidelines lack definitive evidences about the relative benefits of locoregional surgery for the primary tumor in de novo stage IV breast cancer. The aim of this study (SYSBTC-001) was to investigate the role of locoregional surgery for primary tumor in de novo stage IV breast cancer.

invasive breast cancer
metastasis
cancer
breast cancer
stage iv breast cancer
  • 0 views
  • 16 Feb, 2024
  • 3 locations
PRISM: Patient Experiences With PET Imaging in Prostate Cancer (PRISM)

The purpose of this study is to examine patient experiences, health-related quality of life, and decision-making associated with PET imaging for prostate cancer. In particular, Prostate Specific Membrane Antigen (PSMA) PET, a new and more sensitive form of imaging that can help identify metastatic cancer earlier and more reliably.

  • 0 views
  • 05 Nov, 2025
Determination of Blood Tumor Cells

Magnetic nanoparticles coated with anti-EpCAM or anti-CD52 antibodies will be tested ex-vivo in patients blood .

hematologic malignancy
cancer
lymphoma
leukemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

Background Adrenocortical cancer (ACC) is a rare tumor. The prognosis is very poor for people with advanced stages of ACC. Some people may live with ACC for years; others live for just months.

adrenocortical carcinoma
solid tumors
cancer
adrenal
blood tests
  • 0 views
  • 16 Feb, 2024
  • 1 location
Immune Profiling After HDR in Local Relapsed Prostate Cancer

Immunotherapy is currently revolutionizing the field in oncology. However, prostate cancer until now fails to respond to classical IO, like PD-1 and CTLA-4 inhibitors. Radiotherapy (RT) delivered to the primary tumor impacts both tumor cells and surrounding stromal cells.

tumor cells
brachytherapy
primary tumor
multiparametric magnetic resonance imaging
  • 0 views
  • 16 Feb, 2024
  • 1 location