Found 1815 clinical trials
Immunity and Safety of Covid-19 Synthetic Minigene Vaccine
In this study, the safety and efficacy of this LV vaccine (LV-SMENP) will be investigated.
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- 16 Feb, 2024
- 3 locations
Effects of Brain Stimulation on Cognition Oscillations and GABA Levels in Schizophrenia
Behavioral, electrophysiological (EEG) and neuroimaging measures will be used to assess cognitive performance. This study has three main goals: (1) To compare the effects of task-engaged versus resting tDCS in order to optimize the impact of tDCS on goal maintenance related neural oscillatory activity and task performance in schizophrenia; (2) …
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- 16 Feb, 2024
- 1 location
Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer
How to improve the the efficacy of neoadjuvant therapy is an important clinical problem to be solved. Immunotherapy targeting the PD-1/PD-L1 checkpoints has demonstrated promising activity in advanced EC especially in ESCC.
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- 05 Aug, 2020
Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness
The primary aim of this study is to examine the efficacy of a one-session, hour-long HIPAA-compliant video platform-based mindfulness + compassion telehealth intervention on reducing feelings of loneliness during COVID-19 quarantine. Participants (n=120) currently isolating due to COVID-19 will be randomized to one of three interventions: (a) mindfulness + compassion …
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- 16 Feb, 2024
- 1 location
Reduced Occupational Sitting in Type 2 Diabetes Using mHealth (Mobile Health)
Recent research suggest that reduced sitting and increased physical activity can be supported at a low cost by mHealth (mobile health) technology such as activity tracker armbands that warns of prolonged sitting and SMS text messages that reminds of activity breaks.
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- 16 Feb, 2024
- 1 location
Pelvic Floor Magnetic Stimulation in Women With Idiopathic Overactive Bladder
Moreover, there is no recommendation on conservative treament combinations in the guidelines due to insufficient data. At this stage, studies are needed to determine whether it will be effective to use MS in combination with other conservative treatment options. In addition, in the light of our clinical experience, we think …
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- 16 Feb, 2024
- 1 location
Performance of CAD/CAM Milled and 3D-printed Full-arch Implant-supported Provisionals Restorations
Participants will: Receive milled (control material: PMMA; Multilayer PMMA block, HUGE; Shandong Huge Dental Material Corporation) or printed (test material: 3D impression resin; VarseoSmile Temp, Bego Bremer Goldschägerei Wilh. Herbst GmbH & Co. KG, Bremen) and they will be in provisional phase for 3 months doing daily life. Researchers will …
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- 28 Jul, 2023
- 1 location
Empowering Anxious Parents to Manage Child Avoidance Behaviors
The proposed randomized trial will evaluate the effects of a novel, web-based, self-guided SSI designed to systematically reduce parent accommodation: a parenting behavior identified as a strong risk factor for anxiety in offspring. Study aims will be three-fold: (1) to examine the SSI's direct effects on parental accommodation, relative to …
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- 05 Aug, 2020
Morphological Parameters of In-stent RESTenosis Assessed and Identified by OCT
The investigators propose a prospective, multicentre study of all cases of intrastent restenosis, examined by angiography, causing clinical features involving stable angina and acute coronary syndrome. The coronary artery involved will be routinely studied by OCT for a mechanical cause of the intrastent restenosis. The routine use of intrastent OCT …
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- 16 Feb, 2024
- 1 location
Do Implementation Intentions Increase Average Daily Step Count.
The literature suggests that even minor changes in behavior can reduce the morbidity, mortality and costs to the health care system. Pedometers have proven to be an effective tool for increasing physical activity, and have the potential to create change in health habits. The pedometer measures steps and is a …
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- 16 Feb, 2024
- 1 location