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Found 373 clinical trials
Application of TMS Coupled With VR for Slowing the Rate of Cognitive Decline in Patients With Alzheimer's Disease

This is a randomized sham control study to evaluate how repetitive Transcranial Magnetic Stimulation (rTMS), interactive cognitive training, or the combination of rTMS and cognitive training reduce the cognitive decline of patients diagnosed with Alzheimer's disease

alzheimer's disease
cognitive training
ischemia
cognitive decline
mental state examination
  • 0 views
  • 05 Aug, 2020
Education Program for Care Home Staff

The competence of care home staff in dementia care is highly influential to the quality of care that adversely affects both people living with dementia and staff and in Mainland China where knowledge on dementia among care home staff was generally poor and this area is under-researched.

dementia
  • 0 views
  • 05 Aug, 2020
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad

Disturbed sleep is stressful to persons living with dementia (PLwD) and their caregivers. It contributes to earlier placement of the PLwD in nursing homes and increase the risk for many psychological and cognitive health issues and poor quality of life for both the PLwD and the caregivers.

alzheimer's disease
behavior modification
hearing impairment
psychotropic drugs
sleep disorder
  • 0 views
  • 16 Feb, 2024
  • 2 locations
PTI-125 100 mg for Mild-to-moderate Alzheimer's Disease Patients

An Open-label study for patients who completed the previous studies, PTI-125-02 or PTI-125-03. Additional new patients will be included for a total of 100 patients enrolled for this study.

alzheimer's disease
mini-mental state examination
amyloidosis
donepezil
galantamine
  • 0 views
  • 16 Feb, 2024
  • 9 locations
Supporting Family Caregivers of Persons Living With Dementia: Effectiveness and Sustainability of MT4C-In Care

When a person living with dementia moves into a long term care facility, their family members remain involved in their care. They learn new roles and make significant and often stressful adjustments.

dementia
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Orange Juice and Glycaemic Control in Type 2 Diabetes Mellitus

The aim of the project is to study the impact of the intake of a single serving of 100% orange juice on glycaemic control in male patients with pre-existing type 2 diabetes mellitus. In addition, immunological parameters and Alzheimer disease related biomarkers will be assessed to examine the chronic inflammatory …

plasma glucose
  • 0 views
  • 05 Aug, 2020
Equality in Caregiving

The primary goal of this pilot clinical trial is to establish the readiness of an intervention addressing the unique challenges facing lesbian, gay, bisexual, and transgender (LGBT) informal caregivers of person living with dementia (PLWD), and geared toward achieving caregiver mastery in this high-risk population, for a larger efficacy trial.

dementia
  • 0 views
  • 05 Aug, 2020
Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by double-blind, randomized adjunctive treatment with clonazepam or pregabalin for persistent symptoms.

depressive disorder
anxiety
oral contraceptives
clonazepam
escitalopram
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease

This study is a multicenter, double blind, randomized, placebo-controlled study to evaluate the safety, tolerability and immunogenicity of different doses, regimens and combinations of Tau targeted vaccines in participants with early Alzheimer's Disease.

alzheimer's disease
dementia
mild cognitive impairment
amyloidosis
acetylcholinesterase
  • 0 views
  • 05 Aug, 2020
A Daily-Activity-Focused, Strategy-Based Educational Programme for Informal Dementia Carers

This study will assess the impact of the Dementia Carer Education Programme on the caregiving burden of informal dementia carers.Ninety informal dementia carers along with their care-recipients will be recruited and randomised to the experimental and control groups.

  • 0 views
  • 16 Jun, 2025