Found 332 clinical trials
Investigating National Solutions for Personalised Iodine-131 Radiation Exposure
This is a single-arm non-interventional prospective observational study to perform quantitative I-131 imaging and patient-specific dosimetry for patients undergoing radioiodine treatment.
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- 16 Feb, 2024
- 1 location
Observational Study of Intra-operative Partial Irradiation of Invasive Ductal Breast Carcinomas With a Good Prognosis
This APBI technique has been developing in France over the past 5 years within the framework of clinical studies and in compliance with the 2012 recommendations of the French National Cancer Institute. This APBI can be given by 3D external radiotherapy or, as in this study, by intra-operative radiotherapy (IORT) …
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- 05 Aug, 2020
Urinary and Sexual Dysfunctions Evaluation After Rectal Resection
Moreover, no data are currently present regarding the impact of pre-operative chemo-radiotherapy on the urinary and sexual functionalities. The main objective of the investigator's prospective study will be to define in a subjective manner which technique (open, laparoscopic, robot-assisted and Ta-TME) will guarantee the best urinary and sexual outcomes after …
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- 05 Aug, 2020
Effect of Different Treatments on the Prognosis of Early Cervical Cancer: A Multicenter Prospective Real-world Study
To observe the effects of different treatments on the oncological outcome and complications of early cervical cancer (2018 FIGO stage IA1 with lymphovascular space invasion and IA2-IIA2 cervical cancer). This study prospectively collecting enrolled cervical cancer patients clinical data and outcome from June 2020 to June 2025. (Classification factors: preoperative …
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- 16 Feb, 2024
- 1 location
Staging Endometrial caNcer Based on molEcular ClAssification
The SENECA study tries to evaluate the rate of lymph node involvement depending on the molecular subgroup in early-stage endometrial cancer (I/II) patients undergoing surgery as part of their treatment.
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- 01 Feb, 2023
- 1 location
Early Detection of Cardiac Damage by Two Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy
The purpose of this study is to detecte and predict early subclinical cardiac damage induced by thoracic radiation therapy based on twodimensional speckle tracking echocardiography combined with multiple circulating biomarkers.
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- 16 Feb, 2024
- 1 location
Validity and Reliability of the Turkish Version of the Head and Neck Cancer Inventory
Morbidities resulting from the combined application of radiotherapy and chemotherapy are based on more anecdotal information and critical data on long-term functional outcomes in this patient group are scarce.
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- 16 Feb, 2024
- 1 location
Immune Profiling After HDR in Local Relapsed Prostate Cancer
However, prostate cancer until now fails to respond to classical IO, like PD-1 and CTLA-4 inhibitors. Radiotherapy (RT) delivered to the primary tumor impacts both tumor cells and surrounding stromal cells. Radiation damage to cancer cells exposes tumor-specific antigens leading to increased visibility to the immune system by improved priming …
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- 16 Feb, 2024
- 1 location
Validity and Reliability of the Turkish Version of the Neck Dissection Impairment Index
One of the long-term effects of neck dissection applied to patients with head and neck cancer is shoulder dysfunction, which directly affects the quality of life. Patients complain of different degrees of shoulder joint problems following neck dissection . Shoulder syndrome in these patients is characterized by a set of …
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- 16 Feb, 2024
- 1 location
Cerebral Morbidity After Radiation Therapy for Brain Tumors
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.
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- 16 Feb, 2024
- 4 locations