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Found 1815 clinical trials
Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC)

Due to the lack of evidence for an optimal radiotherapy regimen for an "in-situ vaccination" effect three different radiotherapy regimens will be tested.

gilbert's syndrome
vaccination
cancer
kidney function test
neutrophil count
  • 0 views
  • 16 Feb, 2024
  • 13 locations
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

They will visit NIH every 6 months and repeat the above tests. Participants will be monitored for up to 3 years after they stop taking eltrombopag. They will visit NIH 6 months after treatment ends. If participants blood counts go down after treatment ends, they may restart the drug....

blood transfusion
electrocardiogram
cell counts
corticosteroids
blood cell count
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease Symptoms

Part 3 and Part 4: Participants aged 6 < 12 will receive risankizumab based on body weight. Around 132 participants will be enrolled in approximately 30 sites worldwide. Risankizumab and ustekinumab are given as a subcutaneous (under the skin) injection.

plaque psoriasis
pediatric
blood tests
systemic therapy
ustekinumab
  • 0 views
  • 05 Aug, 2020
The Effects of Low Dose Ketamine on Cardiovascular Function

Prior studies on low dose ketamine have noted short-term (minutes to hours) increases or decreases in blood pressure. Blood pressure that is too high or too low can be problematic if untreated. It is unknown exactly how low dose ketamine affects blood pressure. In fact, no prior studies have measured …

diastolic blood pressure
ketamine
nervous system
depression
analgesia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Feasibility of Minimally Supervised Therapy After Stroke With a Hand Rehabilitation Robot

Minimally supervised therapy means that after a training phase, where the therapists teach to the patients how to perform the exercises with the robot, the patients can autonomously train with the robot during free time without being directly supervised. Our hypothesis is that minimally supervised therapy might be a possible …

ataxia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Directional Subthalamic Deep Brain Stimulation on Gait and Balance in Parkinson's Disease Patients

Ten patients with Patients with severe form of Parkinson's disease eligible to deep brain stimulation of the subthalamic nucleus, will be included in two French sites.

dopa
brain stimulation
estrogen
tubal ligation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Diffusion MRI for Head and Neck Cancer

Previous studies have shown that both diffusion coefficient D and diffusional kurtosis coefficient K are promising imaging markers of (i) cell viability which can be used for evaluation of early treatment response. However, it is often underappreciated that these dMRI metrics are not fixed constants, but rather functions of the …

probe
chemoradiation therapy
cancer
pet/mri
chemoradiotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Vacuum Assisted Biopsy Immediately Before Surgery as an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer

Vacuum-assisted biopsy (VAB) with the possibility of obtaining tissue of the former tumor center could contribute more reliably to detect any residual tumor or respectively, rule out residual disease. Ultrasound (US) or mammographically (MG) guided VAB will be used in this trial in order to detect residual tumor lesions in …

adjuvant chemotherapy
invasive breast cancer
luminal
primary tumor
luminal b breast cancer
  • 0 views
  • 16 Feb, 2024
  • 16 locations
This Study Aim is to Compare the Effect of Oral Methyl Prednisolone on Different Radiological Patterns of Hypersensitivity Pneumonitis as it Was Found That Not All Patients Get Satisfying Therapeutic Effect After Taking Corticosteroids.

Not All Hypersensitivity Pneumonitis Patients get the Same Therapeutic Effect after taking Corticosteroid so by Comparing the Effect of Methyl Prednisolone on Patients With Different Radiological Pattern we Will be Able to Select the Patient Who Really Need to Take Corticosteroid and Who Don't so we Will Protect the Patient …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Diffusion MRI for Head and Neck Cancer

Previous studies have shown that both diffusion coefficient D and diffusional kurtosis coefficient K are promising imaging markers of (i) cell viability which can be used for evaluation of early treatment response. However, it is often underappreciated that these dMRI metrics are not fixed constants, but rather functions of the …

  • 0 views
  • 25 Apr, 2025