Found 1815 clinical trials
Continuous Versus Cyclical OCP Use in PCOS (CCOUP)
These findings will be compared over a 6 month period.
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- 04 Apr, 2022
- 2 locations
Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in Indonesia
This examination will be carried out 4 times: on the first day before the research series, four weeks after giving therapy before cataract surgery, 21 days after cataract surgery, and 90 days after cataract surgery.
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- 10 Jan, 2024
- 1 location
Intratumoral Tilsotolimod a TLR-9 Agonist Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers
Open label, phase Ib study of intratumoral tilsotolimod in combination with intratumoral ipilimumab and intravenous nivolumab. The trial will be divided into two parts: PART A: the first part will assess the safety of two regimen and will recruit patients with all types of injectable solid malignancies PART B: the …
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- 16 Feb, 2024
- 1 location
A Study to Determine the Safety of AV-1 an Antibody Being Developed for Treatment of Dengue in Healthy Volunteers
AV-1 is a human monoclonal antibody (mAb) being investigated as a potential therapy for dengue, a mosquito-borne viral disease with extensive global public health impact. Globally, over 2 billion people are thought to be at risk of infection from the dengue virus and there are an estimated 390 million infections …
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- 16 Feb, 2024
- 1 location
INO-3107 With Electroporation (EP) in Participants With HPV-6- and/or HPV-11-Associated Recurrent Respiratory Papillomatosis (RRP)
Cohort B: Participants with Adult-onset RRP as defined by age at first diagnosis of RRP 12 years. A safety run-in will be performed with up to six participants across cohort A and B with a one week waiting period between each enrolled participant.
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- 05 Aug, 2020
Unacylated Ghrelin to Improve Functioning in PAD
Preliminary evidence suggests that unacylated ghrelin may improve blood flow to the extremities and promote improved skeletal muscle growth and energy use. A total of 30 participants with PAD will be randomized to one of two groups: unacylated ghrelin injections or placebo injections . Participants will self-administer the study drug …
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- 16 Feb, 2024
- 1 location
Different Modalities of Management of Odontogenic Keratocysts (OKCs)
Rationale Through the management of OKC a recurrence could occur, the effectiveness of Decompression/marsupialization (D/M), Enucleation (E), Enucleation+Carnoy's solution chemical cauterization (E+CS), Enucleation+peripheral ostectomy (E+PO), Enucleation+Carnoy's solution chemical cauterization + peripheral ostectomy (E+CS + PO), will be analyzed
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- 30 Nov, 2023
- 2 locations
Role of Inflammasomes in COVID-19 Disease
Activating multiprotein complexes called inflammasomes, which cause pro-IL-1 and pro-IL-18 to be transformed into active pro-inflammatory cytokines are one of these pathways. The central role of inflammasomes in the secretion of these pro-inflammatory cytokines deserves an in-depth study of their activation during COVID-19, whereas the inadequate inflammatory response appears to …
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- 16 Feb, 2024
- 2 locations
A Study To Investigate The Safety Tolerability Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome
Two linked sets of dose escalation cohorts are planned based on two different age groups, namely participants with AS aged 5 to 12 years in cohorts A1 to A4 (with at least 2 participants 8 years old in each cohort) and AS participants aged 1 to 4 years in cohorts …
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- 05 Aug, 2020
Tissue Retractors for Radiation Therapy of Head and Neck Tumors
The most effective approach to reducing acute toxicity is to cut out healthy tissue from the radiation field. The distance between the tumor and normal tissue can be individually increased using personalized, 3D printer-based tissue retractors (GWR). Even the smallest geometric changes lead to a significant dose reduction in normal …
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- 16 Feb, 2024
- 1 location