Found 303 clinical trials
MDD(Mild Cognitive Impairment Delirium Dementia) Cohort Test Comment here in title
Dementia conversion rate and conversion period of subjects with mild cognitive impairment with delirium and it identifies the effect of delirium on dementia conversion. Develop an AI(Artificial intelligence) algorithm for predicting dementia transition in subjects with mild cognitive impairment based on the research results of the 1st, 2nd, and 3rd …
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- 14 Mar, 2022
- 3 locations
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia (Bio-Hermes-002)
Bio-Hermes-002 is a 120-day cross-sectional study that will result in a blood, CSF, retinal, digital, MRI, and PET brain imaging biomarker database that can be used to determine the primary objective. Digital biomarkers and blood-based biomarkers will be tested to determine whether a meaningful relationship exists between biomarkers alone or …
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- 17 Oct, 2025
- 1 location
Eating Habits and Lifestyle Profile of an Italian Aging Cohort
Aging is characterized by low-grade inflammatory state, supported by impairment oxidative balance and endocrine changes, leading to changes in: body composition, such as decrease in lean body mass and increase in adipose tissue; resting metabolic rate; immune function; cognitive impairment. According to the Academy of Nutrition and Dietetics all subjects …
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- 16 Feb, 2024
- 1 location
Management and Outcomes of Patients Admitted to Coronary Care Units Depending on Degree of Frailty and Comorbidities
The Clinical Frailty Scale (CFS) is a global clinical measure of biological age, mixing co-morbidity, disability and cognitive impairment. The investigators have previously reported the potential importance of frailty for short-term (1 month) and medium-term outcome (1 year) in a NSTEMI population.
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- 16 Feb, 2024
- 2 locations
Prevalence and Level of Diagnosis of Dementia in a Population-based Sample in the County of Tr ndelag
To investigate and make valid estimates of the occurrence of dementia and the most common subtypes of dementia in Trndelag, and transfer these figures to estimates of the occurrence of dementia in Norway as a whole, by age, sex and severity of dementia. Furthermore, the proportion of people without dementia …
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- 16 Feb, 2024
- 1 location
Speech Linguistic and Acoustic Markers in Parkinson's Disease
We aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. We will administer various speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls.
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- 16 Feb, 2024
- 1 location
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly
Cognitive complaints are considered a marker able to predict cognitive and functional decline, incident mild cognitive impairment (MCI), and incident dementia. The Gero cohort is the Chilean core clinical project of the Gerocenter on Brain Health and Metabolism (GERO), whose aim is to establish the capacity in Chile to foster …
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- 16 Feb, 2024
- 1 location
Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients
In this observational study, the investigators evaluate the influencing factors of cerebrovascular disease and cognition in hemodialysis patients.
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- 05 Aug, 2020
Cardiac Output, Cerebral Perfusion and Cognition in Patients With Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation (CAPITA)
Rationale: Cardiovascular disease and cognitive diseases are closely related. Cognitive impairment is common (21-39%) among patients with severe aortic valve stenosis. The proof-of-concept CP-TAVI study showed that increased cardiac output following transcatheter aortic valve implantation (TAVI) was associated with increased cerebral blood flow.
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- 11 Jan, 2023
- 1 location
Cerebral Morbidity After Radiation Therapy for Brain Tumors
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.
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- 16 Feb, 2024
- 4 locations