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Found 443 clinical trials
Octagam 10% Therapy in COVID-19 Patients With Severe Disease Progression

This is a randomized, double-blind, placebo-controlled, multicenter, Phase 3 study to evaluate if high-dose Octagam 10% therapy can stabilize or improve clinical status in patients with severe Coronavirus disease

fraction of inspired oxygen (fio2)
pao2
covid-19
pao2/fio2 ratio
coronavirus infection
  • 0 views
  • 05 Aug, 2020
Study of Safety Tolerability and PK PD of HPG1860 in Healthy Subjects

This is a randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of HPG1860 orally administered in healthy subjects.

  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of the Safety and Efficacy of Ciclesonide in the Treatment of Non-hospitalized COVID-19 Patients

The purpose of this study is to assess the safety and efficacy of Alvesco (ciclesonide) Inhalation Aerosol in non hospitalized patients with symptomatic COVID-19 infection in a multicenter, randomized, double-blind, placebo controlled study

cystic fibrosis
corticosteroids
pulmonary fibrosis
hydroxychloroquine
oximetry
  • 0 views
  • 05 Aug, 2020
Postoperative Adjuvant Treatment of Completely Resected Mucosal Melanoma Phase II Study

A mucosal melanoma postoperative adjuvant treatment of multicenter, randomized, double-blind, placebo-controlled phase II study, evaluation of mucosal melanoma patients accept completely resected, Toripalima Combined with Temozolomide and Cisplatin postoperative adjuvant therapy efficacy and safety

adjuvant
melanoma
cisplatin
adjuvant therapy
PET-CT
  • 0 views
  • 05 Aug, 2020
A Safety Tolerability and Efficacy of EIDD-2801 to Eliminate Infectious Virus Detection in Persons With COVID-19

This is a phase IIa, double-blind, placebo-controlled, randomized trial, designed to compare the safety, tolerability, and antiviral activity of EIDD-2801 versus placebo as measured by infectious virus detection in symptomatic adult outpatients with COVID-19

anosmia
chills
sore throat
antiviral drugs
congestion
  • 0 views
  • 01 Feb, 2023
  • 1 location
Treatment With CSL312 in Adults With Coronavirus Disease 2019 (COVID 19)

This is a prospective, phase 2, multicenter, randomized, double blind, placebo controlled, parallel group study to assess the safety and efficacy of CSL312 administered intravenously, in combination with standard of care (SOC) treatment, in patients with Coronavirus disease 2019 (COVID 19)

pao2
oximetry
administered intravenously
chest ct
FIO2
  • 0 views
  • 05 Aug, 2020
SCB-2019 as COVID-19 Vaccine

This is a randomized, double blind, placebo controlled, first-in-human (FIH) study to assess safety, reactogenicity, and immunogenicity of SCB-2019 at multiple dose levels, administered as 2 injections IM in healthy subjects.

follicle stimulating hormone
bilateral oophorectomy
hysterectomy
vaccination
electrocardiogram
  • 0 views
  • 05 Aug, 2020
A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia

This is a Phase II, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of MSTT1041A (astegolimab) or UTTR1147A in combination with standard of care (SOC) compared with matching placebo in combination with SOC in patients hospitalized with severe coronavirus disease 2019 (COVID-19) pneumonia.

capillary oxygen saturation
fraction of inspired oxygen (fio2)
pneumonia
ct scan
pao2
  • 0 views
  • 05 Aug, 2020
Efficacy and Safety of Polyoxidonium in Hospitalized Patients With Coronavirus Disease COVID-19

The purpose of this study is to demonstrate the superiority of Polyoxidonium, lyophilizate for solution for injections and topical application, 6 mg over placebo in hospitalized patients with coronavirus disease (COVID-19). This is a multicentre prospective, randomized, double-blind, placebo-controlled, parallel-group phase IIb\IIIa clinical trial.

covid-19
ct scan
coronavirus infection
SARS
chest x-ray
  • 0 views
  • 16 Feb, 2024
  • 12 locations
A First in Human Study to Evaluate the Safety Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects

This is a first in human study of ETD002 a new drug being developed for the treatment of cystic fibrosis.The study is a randomised, double-blind, placebo-controlled, interventional study to assess the safety and tolerability of ascending single and repeat doses of inhaled ETD002 in healthy male and female subjects.

cystic fibrosis
  • 0 views
  • 05 Aug, 2020