Found 31 clinical trials
Investigation of the Effects of Exercise on Patients With Chiari Malformation
Chiari Malformation (CM) is a posterior brain anomaly caused by the displacement of the brain stem and cerebellum into the cervical spinal canal. There are 8 types of Chiari malformations described today that vary according to the severity of the anomaly. In CM Type 1, cerebrospinal fluid (CSF) circulation deteriorated …
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- 16 Feb, 2024
- 1 location
A Study With Pembrolizumab for Non-small Cell Lung Cancer (NSCLC)
This study is a randomized, national multicenter clinical study which is designed to compare the efficacy of the safety and efficacy of treatment every 3 weeks or 6 weeks in (Non-small-cell-cell cancer, NSCLC) subjects without systematic treatment who used Pembrolizumab after 6 cycles of combined chemotherapy estimated with stable efficacy …
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- 05 Aug, 2020
Natural History and Clinical Features of Amyotrophic Lateral Sclerosis (ALS)
Describe the distribution of ALS in mainland China, to explore the differences in the number of ALS in different times, regions and populations in order to further explore the causes affecting the distribution of ALS; To investigate the cause of ALS in mainland China in the crowd disease development process …
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- 05 Aug, 2020
Duke Spine Outcome Study (DSOS)
The primary goal of this registry is to increase the knowledge about spine tumors and other spine disorders to guide appropriate management strategies for the future. This registry will include the review of medical records, data collection for health related quality of life questionnaires, and collected tissues and samples. The …
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- 16 Feb, 2024
- 1 location
Bone-biomarkers of Spinal Cord Injury Patients
Patients with spinal cord injury have a high prevalence of osteoporosis due to chronic skeletal unloading. Recently, various treatment drugs for osteoporosis have been developed.
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- 16 Feb, 2024
- 1 location
Descriptive Study of Acute Spontaneous Spinal Cord Infarction
Acute spontaneous Spinal Cord Infarctions (SCI) are an uncommon cause of myelopathy (5%), but their prognostic is heterogeneous and frequently severe. Positive diagnosis is difficult, one quarter of initial MRIs are normal.
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- 16 Feb, 2024
- 1 location
Effectiveness of the Collaborative Community Clinic for Persons With Spinal Cord Injury and Disease
Researchers seek to evaluate the effectiveness of the Collaborative Community Clinic (CCC), an occupational therapy student experiential learning clinic for uninsured or under-insured people with spinal cord injury and disease (SCI/D), using participants' initial and follow-up assessment batteries.
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- 05 Aug, 2020
Analysis of the Motion Activity Manual Wheelchair Users
Currently, there is no system in place to allow manual wheelchair users to know their quantities of movement activities and the intensity of effort to be provided during these propulsion movements. Based on recent work by Routhier et al. in 2017, and in light of the scientific literature related to …
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- 16 Feb, 2024
- 1 location
The Effect of Midazolam Sedation on Diagnostic Medial Branch Blocks
This prospective observational study aims to investigate the effect of midazolam sedation on the diagnostic validity of diagnostic lumbar medial branch block in patients diagnosed with lumbar spondylosis without myelopathy.
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- 05 Aug, 2020
The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study (Pre-fALS)
Pre-fALS is a prospective natural history and biomarker study of people not yet affected with ALS, but who are at genetic risk for developing ALS. The investigators aim to recruit unaffected (healthy) people from familial ALS (fALS) pedigrees in which a known genetic mutation associated with ALS has been identified; …
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- 01 Feb, 2024
- 1 location