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Found 51 clinical trials
Effect of Minocycline on Delirium Incidence in Critically Ill Patients

It is associated with unfavorable outcomes in hospitalized patients, including longer hospital length of stay, need for subsequent institutionalization and higher mortality rates. Patients in the intensive care unit (ICU) under mechanical ventilation and older age are at higher risk for the development of delirium. Several studies suggest that minocycline, …

dementia
agitation
abuse
bdnf
minocycline
  • 0 views
  • 16 Feb, 2024
  • 1 location
Dexamethasone for COVID-19 Related ARDS: a Multicenter Randomized Clinical Trial

There is compelling data indicating that there is an excessive inflammatory response in some patients with COVID-19 leading them to develop ARDS that can be severe with a very poor prognosis. Many of these patients require very long mechanical ventilation times to survive, which have led to the collapse of …

acute respiratory distress
SARS
inflammatory response
respiratory infection
corticosteroids
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19

Early data from the Covid-19 pandemic suggest a high incidence of critically ill patients admitted to intensive care units (ICU) will require mechanical ventilation for acute respiratory failure. Covid-19 patients surviving an admission to the ICU are expected to suffer from physical and cognitive impairments that will limit quality of …

depression
weakness
critically ill
cognitive impairment
attrition
  • 0 views
  • 16 Feb, 2024
  • 1 location
Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma

This study aims to collect convalescent plasma and use it as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit.

acute respiratory distress syndrome
acute respiratory distress
organ failure
critically ill
shock
  • 0 views
  • 05 Aug, 2020
Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients

it will be conducted a randomized parallel controlled trial with patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) to compare two techniques to lung recruitment and cough augmentation, to assess their effects on pulmonary function, global functionally, swallowing and ability to speech in these population.

cough
primary lateral sclerosis
mini-mental state examination
neuromuscular diseases
amyotrophic lateral sclerosis
  • 0 views
  • 16 Feb, 2024
  • 1 location
External Dead Space in Ventilated COVID-19 Patients

The objective is to investigate the efficacy of volumetric capnography to detect changes in dead space, CO2 elimination and shape factor parameters before and after disconnection of external dead space in ventilated COVID-19 patients.

covid-19
mechanical ventilation
  • 0 views
  • 05 Aug, 2020
Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique

COVID 19 is a novel and severe disease. One of the problems is that the virus disturbs the lungs and cause water accumulation in lungs alveolus (ARDS). Today, a chest X-ray is the only practical way to check the degree of lung accumulation. However, X-Ray has many limitations and disadvantages. …

covid-19
acute respiratory distress
respiratory distress
x-rays
chest x-ray
  • 0 views
  • 05 Aug, 2020
Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia

2019 new coronavirus (2019-nCoV) infected pneumonia, namely severe acute respiratory infection (SARI) has caused global concern and emergency. There is a lack of effective targeted antiviral drugs, and symptomatic supportive treatment is still the current main treatment for SARI. Vitamin C is significant to human body and plays a role …

pneumonia
antiviral drugs
respiratory infection
respiratory tract infection
coronavirus infection
  • 0 views
  • 16 Feb, 2024
  • 1 location
Heart Transplantation Using Normothermic Regional Perfusion Donation After Circulatory Death

Normothermic regional perfusion (NRP) utilizes Extracorporeal Membrane Oxygenation (ECMO) or cardiopulmonary bypass to reperfuse the heart and other organs in situ after isolation and ligation of the cerebral vessels. In situ resuscitation of the heart has the added advantage of allowing full hemodynamic and echocardiographic assessment of the donor heart …

heart transplantation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants

The aim of the project is to study the effects of fortification (using a Human Milk Donor Fortifier) of an exclusive preterm human milk diet on outcome of extremely preterm neonates, born at less or equal to 27 weeks.

enteral feeding
  • 0 views
  • 16 Feb, 2024
  • 1 location