Found 401 clinical trials
Tofacitinib for Treatment of Moderate COVID-19
The purpose of this randomized, double blinded, placebo controlled study is to assess the efficacy and safety of tofacitinib in hospitalized adult (18-65 years old) patients with SARS-CoV-2 and pneumonia who require supplemental oxygen and have serologic markers of inflammation but do not need mechanical ventilation.
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- 05 Aug, 2020
Low Dose Radiotherapy for COVID-19 Pneumonitis
SARS-CoV-2 is causing an unprecedented stress on healthcare systems around the world, due to its high rate of infection and the high morbidity and mortality. The COVID-19 infection triggers an inflammatory cascade with cytokine synthesis, prompting the immune response. Low dose radiotherapy (LD-RT) ( 100 cGy) induces an anti-inflammatory response, …
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- 05 Aug, 2020
Role of Inflammasomes in COVID-19 Disease
As of March 25, 2020, 414,179 cases and 18,440 deaths secondary to Coronavirus 2019 disease (COVID-19) have been reported worldwide. The unfavorable course of the patients is characterized on the immunological level by an intense pro-inflammatory response which can go as far as a cytokinic storm.
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- 16 Feb, 2024
- 2 locations
Cyclosporine in Patients With Moderate COVID-19
Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.
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- 16 Feb, 2024
- 1 location
Ivermectin and Doxycycine in COVID-19 Treatment
Efficacy of Ivermectin and Doxycycline in COVID-19 treatment
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- 16 Feb, 2024
- 1 location
Colchicine Plus Phenolic Monoterpenes to Treat COVID-19
In this study, defined cases of COVID-19 with mild, moderate or severe pneumonia will be treated with standard treatment regimens in combination with oral administration of Colchicine Plus Herbal phenolic monoterpene Fractions.
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- 05 Aug, 2020
Convalescent Plasma for the Treatment of COVID-19
This protocol provides access to investigational convalescent plasma for patients in acute care facilities infected with SARS-CoV-2 who have severe or life-threatening COVID-19, or who are judged by a healthcare provider to be at high risk of progression to severe or life-threatening disease. Following provision of informed consent, patients will …
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- 16 Feb, 2024
- 1 location
Hemostasis in COVID-19: an Adaptive Clinical Trial
Hypercoagulability has been demonstrated in COVID-19, leading to respiratory distress and increased mortality. This is adaptive clinical trial to compare effectiveness and safety of four therapeutic strategies in hospital mortality in patients with COVID-19: standard prophylaxis, therapeutic dose anticoagulation, inhaled UFH associated with standard prophylaxis and ASA associated with standard …
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- 16 Feb, 2024
- 1 location
HSS Covid-19 Antibody Serology Among Surgeons & Anesthesiologists
The goal of this study is to understand the infectious exposure of SARS-coronavirus 2 (SARS-CoV2) among surgeons and anesthesiologists and to correlate this status with self-reported indices of COVID-19 illness.
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- 16 Feb, 2024
- 1 location
COVID-19 Convalescent Plasma for Mechanically Ventilated Population
The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it can improve patients' health when they are sick with COVID-19.
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- 16 Feb, 2024
- 1 location