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Found 194 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

apolipoprotein e4
alzheimer's disease
mental state examination
mini-mental state examination
  • 32 views
  • 16 Feb, 2024
  • 127 locations
Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome (HBPCOVID02)

This study will enroll up to 80 subjects with Chronic Post COVID-19 Syndrome. Subjects will receive four intravenous injections of either allogeneic HB-adMSC's or a placebo over 10 weeks with two follow-up visits and an end of study visit at week 26.

  • 0 views
  • 10 Nov, 2022
  • 1 location
A Randomized Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH

A randomized, double-blind study to assess the safety and efficacy of EDP-305 in subjects with liver-biopsy proven Non-Alcoholic Steatohepatitis (NASH)

hcv infection
fatty liver
fibrosis
steatosis
hepatitis b surface antigen
  • 0 views
  • 05 Aug, 2020
A Phase II Randomized, Double-blind, Placebo-controlled, Multi-center, Multi-dose Study to Evaluate Safety and Efficacy of ASC40 Tablets in Subjects With Moderate to Severe Acne Vulgaris.

This is a phase2, randomized, double-blind, multi-center, multi-dose and placebo parallel controlled design. The subjects in the study group were given double-blind drugs, and they were taken (orally) after dinner every day according to the requirements of clinical trial scheme.

  • 0 views
  • 10 Oct, 2022
  • 1 location
A Randomized, Double-blind, Positive-drug Parallel Controlled, Multicenter Phase III Trial of the Efficacy and Safety of S086 Tablets in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)  

A randomized, double-blind, positive-drug parallel controlled, multicenter phase III trial of the efficacy and safety of S086 tablets in patients with chronic heart failure with reduced ejection fraction (HFrEF)

  • 0 views
  • 26 Sep, 2022
  • 5 locations
Mobility Protocol Adapted for Advanced Visually Impaired Subjects

Retinitis Pigmentosa is characterized by a progressive disappearance of photoreceptors, responsible for a progressive and severe loss of vision. People Retinitis Pigmentosa therefore encounter a large number of difficulties in daily life, specifically for: Visual research Visuo-motor coordination in tasks requiring fine motor control Visuo-motor coordination in mobility tasks This …

cognitive disorders
retinitis
low vision
visual impairment
amblyopia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluation of Safety Tolerability and Pharmacokinetics of Single Dose of PF-06480605 in Japanese Healthy Participants

This is a Phase 1, randomized, double-blind, third-party open (ie, participant-blind, investigator-blind and sponsor-open), placebo-controlled, dose escalating clinical study to evaluate the safety, tolerability, immunogenicity, PK and PD of PF-06480605 in Japanese healthy adult participants.

vaccination
12 lead electrocardiogram
drug test
blood donation
coronary artery disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Trial With the Treatment of Sertraline in Youth With Generalized Separation and/or Social Anxiety Disorders.

A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.

nuvaring
adjustment disorder
anxiety
progestin
psychosis
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Single-dose/Multiple-doses Incremental Intravenous Injection of SY-005 in Healthy Subjects

This is a single-dose/multiple-doses incremental, randomized, double-blind, parallel, placebo-controlled study on safety, tolerance and pharmacokinetics healthy subjects.

body mass index
  • 0 views
  • 16 Feb, 2024
  • 1 location