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Found 30 clinical trials
Evaluation of a TDM Program for Intensive Care Patients in the Cerebrospinal Fluid

This study is a prospective study to evaluate the concentration of different antibiotics in the CSF in patients with an external ventricular drainage compared to antibiotic blood concentration.

  • 0 views
  • 05 Aug, 2020
Outcome After Revisions of Infected Knee Arthroplasties

A prospective multicenter cohort study on all types of revision knee arthroplasty procedures performed due to infection.

  • 0 views
  • 05 Aug, 2020
Leptospirosis Registry Gathers Knowledge on Epidemiology Clinical Course Prognostic Factors and Molecular Characteristics for Invasive Leptospirosis Disease

Leptospirosis is a worldwide zoonotic diseases caused by pathogenic Leptospira spp. Human are accidental hosts, who acquired infections after exposition to animal urine, contaminated water or soil, infected tissue. Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Analgetics vs Analgetics and Antibiotics for Pediatric Clinical and Sonographic Orchitis or Epididymitis

Some children are admitted to pediatric emergency department due to epididymitis or orchitis. Some of them are treated by analgetics only whie some are treated by analgetics with antibiotics. The study will compare clinical presentation between groups and will compare pediatric urologic outpatient clinic follow up findings.

antibiotic therapy
pediatric
antibiotics
orchitis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Scandinavian Diverticulitis Trial SCANDIV-II

This study focuses on the treatment for complicated diverticulitis classified as Hinchey I-IV. The aim of this prospective observational study is to evaluate type of treatment and the success rate of treatment in acute complicated diverticulitis (ACD) at participating hospitals in Sweden and Norway. Furthermore, the effects on quality of …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Tissue Models for Liver Disease (TIMOLD)  

The human immune response to bacterial and viral local and systemic infection are fairly well understood, but we lack details on the earliest phases. Better knowledge of these events would be important for the prevention and treatment of severe bacterial or viral disease. From models of infection, we have data …

  • 0 views
  • 24 May, 2022
  • 1 location
Antibiotic Dosing in Geriatric Patients at the Emergency Department

In this pilot study, we will investigate whether - with the current dosing regimens, used in the Ghent University Hospital - pharmacodynamic targets regarding beta-lactam antibiotics (more specific Amoxicilline-Clavulanate, Piperacillin-Tazobactam and Temocillin) are attained in frail patients admitted to the geriatric department.

antibiotics
lactam
piperacillin-tazobactam
piperacillin
lactam antibiotics
  • 0 views
  • 16 Feb, 2024
  • 1 location
Creatinine Clearance as a Predictor of Successful Withdrawl of Continuous Renal Replacement Therapy in Intensive Care

The use of CRRT exposes patients to some complications (bleeding, hemodynamic instability, antibiotic underdosing, malnutrition and infections), justifying the importance of optimizing the quality and reliability of this technique.

  • 0 views
  • 05 Aug, 2020
The Microbiome of Pancreatic Cancer: "PANDEMIC" Study

Microbiome in patients affected by pancreatic ductal adenocarcinoma may present specific and identifiable patterns. These variations could affect the surgical outcome and increase the risk of life-threatening infections supported by multidrug-resistant bacteria. The identification of microbial signatures with tumor specificity may have a potential role in postoperative risk stratification. Variation …

pdac
pancreatic ductal adenocarcinoma
cancer
pancreatic cancer
adenocarcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

In light of the rapidly emerging pandemic of SARS-CoV-2 infections, the global population and health care systems are facing unprecedented challenges through the combination of transmission and the potential for severe disease. Acute respiratory distress syndrome (ARDS) has been found with unusual clinical features dominated by substantial alveolar fluid load. …

lower respiratory tract infection
acute respiratory distress
inflammatory response
endothelial dysfunction
superinfection
  • 0 views
  • 16 Feb, 2024
  • 1 location