Found 364 clinical trials
Cognitive Behavioural Therapy (CBT) for Chronic Loneliness in Children and Young People
Participants will then complete an average of 12 sessions of CBT, with the aim being to reduce their feelings of loneliness over 12 weeks. Participants will then complete a 12-day post-intervention phase. Participant loneliness will be repeatedly assessed throughout the three phases of the intervention using the Three-item Loneliness Scale, …
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- 09 Dec, 2021
- 1 location
Happy Hands Pilot Study
In this pilot study we will assess usability of a e-self-management program for patients with hand osteoarthritis through the Happy Hands app. People with hand osteoarthritis will be recruited for the study. The e-self-management intervention consists of informational videos and videos of hand exercises and has a duration of 12 …
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- 09 Dec, 2021
- 2 locations
A Phase I Trial of Intranasal Peptide T: Safety, Toxicity, and Pharmacokinetics in Human Immunodeficiency Virus-1 (HIV-1) Infected Patients.
To study the safety and toxicity of intranasal peptide T (D-Ala-1-peptide-T-amide) in humans, and to find out how quickly and how much of a given dose enters the bloodstream and how quickly it leaves the bloodstream. To obtain information on the ability of intranasal peptide T to prevent, halt, and/or …
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- 16 Jul, 2025
- 3 locations
To Evaluate the Safety and Pharmacokinetics of Parscaclisib in Participants With Normal Hepatic Function and Hepatic Impairment.
The purpose of the study is to evaluate the pharmacokinetics and safety of parsaclisib in participants With normal hepatic function and participants with hepatic impairment.
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- 10 Sep, 2024
- 3 locations
Automated Insulin Delivery Amongst Pregnant Women With Type 1 Diabetes (AiDAPT)
Evaluation of the biomedical and psychosocial impact of automated Closed-Loop (Artificial Pancreas) insulin delivery in women with type 1 diabetes during pregnancy
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- 09 Sep, 2022
- 1 location
DemoStudyfor V4.6 Sprint Demo (CARGOx)
The differential diagnosis of central diabetes insipidus (cDI) is difficult and the current test with the highest diagnostic accuracy is copeptin measurement after hypertonic saline infusion (HIS). Although the HIS improved diagnostic accuracy compared to the standard water deprivation test used for decades before, it still comprises great discomfort for …
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- 11 May, 2022
- 6 locations
Acceptance and Commitment Therapy for PTSD and Chronic Pain
The primary aim of this study is to investigate the effect of Internet-delivered Acceptance and commitment therapy for PTSD and comorbid chronic pain using a randomized controlled trial with waitlist control.
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- 06 Nov, 2025
- 2 locations
Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation (IMPACT-D)
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).
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- 17 Oct, 2025
Screening Women With Prior HPV for Anal Neoplasia (SWAN)
The goal of this single arm trial is to prospectively evaluate screening methods for anal cancer precursors in HIV uninfected women with a history of lower genital tract neoplasias and cancers.
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- 10 Feb, 2026