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ESM-derived Personalised Feedback for Women at Risk of Depression

This study aims to examine the effectiveness of Experience Sampling Method (ESM) derived personalised feedback for women at risk of depressive disorder in Hong Kong, in reducing individuals depressive symptoms.

A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)

The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.

A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder

The purpose of the study is to evaluate the effect of seltorexant, compared to placebo, as an add-on medication to an antidepressant, on next-day driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) from an on-road driving test.

A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression

The main objectives of this trial are to evaluate the efficacy and safety of oral BI 1358894 compared to placebo over a 6-week treatment period in participants with Major Depressive Disorder (MDD) and with inadequate response to antidepressants (SSRI or SNRI) utilizing a decentralized clinical trial (DCT) model.