Found 287 clinical trials
Asthma: Phenotyping EXacerbations
The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …
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- 16 Feb, 2024
- 1 location
Cancer Therapy Effects on the Heart
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death.
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- 16 Feb, 2024
- 1 location
Clinical Performance of Withings Move ECG Software for Atrial Fibrillation Detection
Withings Move ECG watch is designed to record ECG and detect automatically atrial fibrillation. The aim of this study is to validate the performance of Move ECG watch to detect atrial fibrillation compared to a reference 12-lead ECG.
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- 16 Feb, 2024
- 3 locations
Towards Targeting the ORigin of the Inflammatory Cascade in Allergic Asthma
Allergic asthma is a complex and heterogeneous disease caused by excessive responses to inhaled allergens. Current medication, including corticosteroids and bronchodilators, does not act on the origin of inflammation but rather combats symptoms, leaving many patients uncontrolled. Airway epithelium is critical for the initiation and progression of asthma pathology. We …
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- 16 Feb, 2024
- 1 location
Evaluating Pulse Oximetry Bias in Children With Darker Skin Pigmentation
Studies in adults suggest pulse oximeters may overestimate the true level of oxygenation in the blood as measured directly by co-oximetry. However, pediatric data are relatively limited. This study, which is funded by the FDA through the Stanford-UCSF (University of California San Francisco) Clinical Excellence in Regulatory Science and Innovation …
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- 16 Dec, 2022
- 1 location
A Pilot Study to Explore the Role of Gut Flora in Eczema
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding eczema.
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- 16 Feb, 2024
- 1 location
Validation Study of WITHINGS BPM Core for the Detection of Atrial Fibrillation
The proposed clinical study aims to validate the diagnostic performance, compared to a reference ECG, of the electrocardiographic function of the BPM Core developed by Withings for the automatic identification of atrial fibrillation (AF).
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- 16 Feb, 2024
- 2 locations
Impact of Hybrid Closed-Loop Systems on Sleep and Psychosocial Outcomes in Youth With T1D and Their Parents
This study evaluates the impact of the hybrid closed-loop insulin delivery systems on sleep in youth with type 1 diabetes and their parents. Activity watches, surveys and device downloads are used to evaluate sleep in these participants.
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- 16 Feb, 2024
- 1 location
Use of Dexcom G6 in Commercial Pilots With Insulin Treated Diabetes
The investigators wish to explore the use of the CGMS Dexcom G6 in pilots with insulin-treated diabetes, who are flying commercial aircraft with Class 1 and flying instructors or private pilots with class 2 certificates. The aim of this study is to explore the severity and number of hypoglycaemic episodes …
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- 05 Aug, 2020
Effect of Dulaglutide on Glycemic Variability in Patients With Type 2 Diabetes
Glycemic variability will be assessed using continuous glucose monitor(CGM) in type 2 diabetic patients who receive dulaglutide 1.5 mg/qw injection for 4 weeks.
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- 16 Feb, 2024
- 1 location