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Found 263 clinical trials
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

castration-resistant prostate cancer
apalutamide
adenocarcinoma
testosterone
gonadotropin releasing hormone
  • 0 views
  • 05 Aug, 2020
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

castration-resistant prostate cancer
combined modality therapy
enzalutamide
testosterone
prostatic neoplasms, castration-resistant
  • 0 views
  • 16 Feb, 2024
  • 22 locations
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death. Furthermore, many men with notably advanced disease have been …

castration-resistant prostate cancer
stage ivb prostate cancer ajcc v8
metastatic malignant neoplasm
prostate carcinoma
testosterone
  • 0 views
  • 16 Feb, 2024
  • 1 location