Found 276 clinical trials
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
The study is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental health disorders. Using cluster …
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- 16 Feb, 2024
- 1 location
tDCS Intervention on Motivational Anhedonia of Major Depressive Disorder
Study of tDCS intervention on motivational anhedonia of Major Depressive Disorder
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- 16 Feb, 2024
- 1 location
Virtual Reality Behavioral Activation: An Intervention for Major Depressive Disorder
The primary purpose of this study is to test the safety and feasibility of virtual reality (VR) technology in the use of behavioral activation (BA) as a treatment for major depressive disorder (MDD). The secondary purpose of this study is to examine whether any evidence of clinical efficacy exists for …
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- 16 Feb, 2024
- 1 location
Safety of Liposom With Citalopram in Elderly Patients With Major Depressive Disorder
The purpose of this study is to determine if Liposom Forte will enhance the response to antidepressant therapy with citalopram in elderly patients suffering from Major Depressive Disorder (MDD).
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- 11 Oct, 2021
- 16 locations
testslug trial title
Major depressive disorder (MDD) is a common, recurrent, and frequent chronic disorder. Treatment is often challenging; up to 40% of patients do not benefit sufficiently from existing antidepressant interventions including trials of medication and psychotherapy.
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- 09 Jul, 2021
Effectiveness of Walking Exercise in Improving Depression in Older Adults With Major Depressive Disorder A Pilot Study
This pilot randomized controlled trial aims at investigating the effects of different intensities of aerobic walking exercise to alleviate depression in older adults with major depressive disorder. Both baseline and post-intervention measurements will be conducted at the Exercise Physiology Laboratory, Division of Kinesiology, School of Public Health, The University of …
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- 05 Aug, 2020
Ketamine or Placebo in Patients With Major Depression and Advanced Cancer
Major depression (MD) is a psychiatric disorder characterized by a persistent feeling of sadness, anhedonia or a decreased perception of pleasurable experiences, as well as appetite alterations and weight variations, sleep disorders, altered psychomotor skills, fatigue, guilt, decreased self-worth, suicidal thoughts and difficulty concentrating in a task (1).
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- 16 Feb, 2024
- 1 location
RCT for Electroconvulsive Treatment Followed by Cognitive Control Training
Major depressive disorder (MDD) is worldwide one of the most prevalent and disabling mental health conditions. Electroconvulsive therapy (ECT) is a safe and effective treatment even though 6-month relapse rates are high.
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- 05 Aug, 2020
Mechanism of Action of Transcranial Magnetic Stimulation
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
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- 16 Feb, 2024
- 1 location
Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic
The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose aiTBS protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with unipolar depression previously responsive to ECT and patients needing urgent treatment due to symptom severity during the COVID-19 pandemic.
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- 16 Feb, 2024
- 1 location