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Found 275 clinical trials
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A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

renal cell carcinoma
carcinoma
karnofsky performance status
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic).

aptt
beta human chorionic gonadotrophin
absolute neutrophil count
primary tumor
liver metastasis
  • 8 views
  • 05 Aug, 2020
  • 1 location
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Localized Renal Tumor

This may help doctors and patients with renal tumors in the future to make better treatment decisions.

kidney tumor
aggressiveness
estimated creatinine clearance
MRI
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

kidney function test
cancer treatment
BRAF
immunostimulant
solid tumour
  • 0 views
  • 05 Aug, 2020
CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer  

This phase I trial evaluates the effects of CBM588 in combination with standard therapies, nivolumab and cabozantinib, in treating patients with kidney cancer that has spread to other places in the body (advanced/metastatic). The digestive microbiome may have an effect on how patients respond to treatment, and previous research shows …

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  • 14 Mar, 2022
  • 1 location