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Found 274 clinical trials
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  • 17 Nov, 2021
  • 1 location
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

The BREAKFAST trial will evaluate the antitumor activity of combining cyclic fasting-mimicking diet (FMD), which reproduces the in vitro effects of glucose starvation, plus/minus metformin with standard preperative anthracycline-taxane chemotherapy in patients with stage I-III TNBC

direct bilirubin
HER2
anthracyclines
curative surgery
conjugated bilirubin
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  • 16 Feb, 2024
  • 1 location
Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis

This is an open-label, randomized study comparing a monitored ketogenic diet intervention using standard ketogenic diet (SKD) and standard of care (SOC) dietary recommendations for 16 weeks. Subjects enrolled in the standard of care group will receive a voucher to Weight Watchers after study completion.

fatty liver
ketogenic diet
cirrhosis
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  • 16 Feb, 2024
  • 1 location
LYT-100 in Healthy Volunteers and BCRL

Part 1 is a multiple ascending dose trial in healthy volunteers (HV) of LYT-100 to determine safety, tolerability, and pharmacokinetic (PK) profile under fed conditions. Part 2 is a single dose safety, tolerability, and PK trial in HV of LYT-100 under fasted conditions. Part 3 is a trial of up …

metastasis
secondary lymphedema
HER2
adjuvant
nipple reconstruction
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  • 16 Feb, 2024
  • 1 location
Oil Consumption and Cholesterol

More than 31 million U.S. adults have high total cholesterol and over 73 million U.S. adults have high LDL cholesterol. Cottonseed oil (CSO) is found readily in our food supply, and recent research has shown improvements in blood lipids following CSO consumption in healthy adults with normal cholesterol profiles. To …

hypercholesterolemia
blood lipids
LDL Cholesterol
body mass index
cholesterol measurement
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  • 16 Feb, 2024
  • 1 location
Diets Enriched With Pecans

Background: Previous studies report that daily pecan consumption reduces cholesterol in healthy adults while promoting weight maintenance. Purpose: To examine the impact of daily pecan consumption with and without dietary substitution instructions for an 8-week period on markers of health in adults at risk for cardiovascular disease.

cardiovascular disease
cholesterol level
LDL Cholesterol
cholesterol measurement
low density lipoprotein
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  • 16 Feb, 2024
  • 1 location
Long-term Consumption of Resistant Starch Type-4 (RS4)

The primary objective of the current proposal is to determine the effectiveness of long-term consumption of Fibersym RW for improving blood lipids (including cholesterol) and body composition. The overall goal of this clinical research is to determine the potential effects that RS4 consumption may have on the prevention of obesity …

blood lipids
cholesterol measurement
LDL Cholesterol
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  • 16 Feb, 2024
  • 1 location
Cocoa/Carob Polyphenols and Postprandial Changes in Type 2 Diabetes

The aim of this is study is to evaluate the effects of a single intake of a mixture of cacao and carob (rich in high molecular weight polyphenols) in postprandial metabolism in subjects with type 2 diabetes. Studies on the effects of polyphenols on postprandial (glucidic and lipidic) metabolism have …

polyphenol
metformin
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  • 16 Feb, 2024
  • 1 location
Development of a Simple Fast and Portable Recombinase Aided Amplification Assay for 2019-nCoV

In late December 2019, several local health facilities reported clusters of patients with pneumonia of unknown cause that were epidemiologically linked to a seafood and wet animal wholesale market in Wuhan, Hubei Province, China. It is now confirmed that the etiology of this outbreak is a novel coronavirus, namely, 2019-nCoV. …

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  • 16 Feb, 2024
  • 1 location
Ultrasound Assessment of Gastric Content in Fasted Pregnant Women

Pulmonary aspiration of gastric content is one of the most feared perioperative complication of general anesthesia. Pregnant women are usually considered as high risk of pulmonary aspiration but there is no epidemiological study evaluating gastric content in pregnant women during the entire gestation periode. The main objective is evaluating prevalency …

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  • 16 Feb, 2024
  • 1 location