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Found 258 clinical trials
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Tofacitinib for Immune Skin Conditions in Down Syndrome

People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug …

dermatitis
psoriasis
herpes zoster
skin disorder
alopecia areata
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  • 16 Feb, 2024
  • 1 location