major depressive disorder Clinical Research Trials

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Found 276 clinical trials

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Phase 3
For adults
Recruiting in 100s
Interventional Study
all
Recruiting

A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)

The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.

scid

psychotherapy

benzodiazepines

anxiolytics

major depressive disorder

0 views
16 Feb, 2024
36 locations

Phase 2
For adults
Recruiting in 100s
Interventional Study
all
Recruiting

A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression

The main objectives of this trial are to evaluate the efficacy and safety of oral BI 1358894 compared to placebo over a 6-week treatment period in participants with Major Depressive Disorder (MDD) and with inadequate response to antidepressants (SSRI or SNRI) utilizing a decentralized clinical trial (DCT) model.

scid

selective serotonin reuptake inhibitors

serotonin reuptake inhibitors

suicide

serotonin and norepinephrine reuptake inhibitors

0 views
16 Feb, 2024
1 location

Multi-country trial
Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder

The purpose of the study is to evaluate the effect of seltorexant, compared to placebo, as an add-on medication to an antidepressant, on next-day driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) from an on-road driving test.

selective serotonin reuptake inhibitors

serotonin reuptake inhibitors

anxiety

norepinephrine

vortioxetine

0 views
16 Feb, 2024
2 locations