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Found 273 clinical trials
A Study of Sintilimab Combined With Apatinib and Capecitabine in Advanced Hepatocellular Carcinoma

This study aims to evaluate the efficacy and safety of Sintilimab (an Anti-PD-1 Inhibitor) combined with apatinib and capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma.

sintilimab
thyroid stimulating hormone
capecitabine
systemic chemotherapy
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Laparoscopic Middle Hepatic Vein Guidance and Traditional Anatomic Hemihepatectomy

The study, entitled "RCT study of laparoscopic middle hepatic venous guidance versus conventional ananatomical hemihepatectomy", was designed to compare the efficacy of two different ananatomical hemihepatectomy procedures under laparoscopy.

hypertension
vascular invasion
metastasis
cirrhosis
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

recurrent hepatocellular carcinoma
stereotactic body radiation therapy
carcinoma
radiofrequency ablation
hepatocellular carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Role of CEUS as a Secondary Diagnostic Modality

To determine the role of contrast-enhanced ultrasound (CEUS) as a second-line imaging modality after gadoxetate-enhanced MRI (Gd-EOB-MRI) for identifying hepatocellular carcinoma (HCC) among at-risks observations.

contrast-enhanced ultrasound
carcinoma
hepatocellular carcinoma
  • 0 views
  • 05 Aug, 2020
A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Plus Lenvatinib in First-line Advanced Hepatocellular Carcinoma

An open-label multi-center phase Ib/II study to evaluate the efficacy and safety of anti-PD-1/CTLA-4 bispecific antibody AK104 plus lenvatinib as the first-line therapy for patients with advanced hepatocellular carcinoma.

carcinoma
lenvatinib
measurable disease
hepatocellular carcinoma
  • 0 views
  • 05 Aug, 2020
Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

This study compares gadolinium contrast-enhanced Abbreviated MRI (AMRI) to standard ultrasound for Hepatocellular Carcinoma (HCC) screening and surveillance in subjects with liver cirrhosis.

carcinoma
hepatocellular carcinoma
cirrhosis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Preliminary Antitumor Activity Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma

The primary objective of this study is to assess the preliminary antitumor activity as indicated by overall response rate (ORR) of tislelizumab in combination with lenvatinib in participants with unresectable locally advanced or metastatic hepatocellular carcinoma (HCC).

cholangiocarcinoma
lenvatinib
cancer
hepatocellular carcinoma
unresectable hepatocellular carcinoma
  • 0 views
  • 05 Aug, 2020
Irreversible Electroporation of Unresectable Liver Tumors

The aim of this study is to evaluate the safety and feasibility of curative intended irreversible electroporation (IRE) in the treatment of liver tumors neighboring major vessels or bile ducts.

hepatoma
liver tumor
irreversible electroporation
biliary tract cancer
metastasis
  • 0 views
  • 05 Aug, 2020
Combined Locoregional Treatment With Immunotherapy for Unresectable HCC.

Efficacy and Safety of Locoregional treatments Combined With PD-1 Inhibitor in Patients With Unresectable Hepatocellular Carcinoma.

pd-1 inhibitor
unresectable hepatocellular carcinoma
sintilimab
carcinoma
microwave ablation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Longitudinal Immune-phenotyping of HCC Following MK-3475

The study comprises a main study of pembro-treated HCC patients and a sub-study of untreated HCC patients. In the main study, patients will be treated with pembrolizumab as neoadjuvant treatment approximately 4 weeks prior scheduled surgery.

blood transfusion
immunomodulator
hepatitis b core antibody
prothrombin
hepatectomy
  • 0 views
  • 16 Feb, 2024
  • 1 location